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部分水平环状软骨上喉切除术:哪些因素会影响拔管后的吞咽结果?一项前瞻性单中心经验。

Partial Horizontal Supracricoid Laryngectomy: Which Factors Impact on Post-decannulation Swallowing Outcomes? A Prospective Single-Center Experience.

作者信息

Grasso Michele, Fusconi Massimo, De Luca Pietro, Camaioni Angelo, Belizzi Mario, Flaccadoro Flavia, Agolli Griselda, Ruoppolo Giovanni, de Vincentiis Marco, Di Maria Domenico, Ralli Massimo, Di Stadio Arianna, Colizza Andrea, Greco Antonio

机构信息

Department of Sense Organs, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.

Otolaryngology Unit, Head and Neck Department, San Giovanni-Addolorata Hospital, Rome, Italy.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):1917-1922. doi: 10.1007/s12070-023-03790-6. Epub 2023 Apr 20.

DOI:10.1007/s12070-023-03790-6
PMID:37636747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10447658/
Abstract

Early decannulation, performed within the first ten days after supracricoid partial laryngectomy, can result in a more rapid recovery of swallowing function with a semisolid bolus in the short term, about 30 days. We selected 20 patients with squamous cell carcinoma of larynx, who underwent supracricoid laryngectomies: 10 cricohyoidopexy (CHP) and 10 cricohyoidoepiglottopexy (CHEP). Staging was pT2 (10 pts), and pT3 (10 pts). Fiberoptic endoscopic evaluation of swallowing was used to assess postoperative swallowing function after a mean of 12 and 22 days from surgery. A modified PAS score (penetration-aspiration scale) was assigned for subtotal laryngectomies. Decannulation occurred after 6.7 ± 2.1 days. Univariate analysis showed that the type of surgery (CHP or CHEP), pT, resection of one arytenoid, and decannulation time are significantly associated with the 12-day PAS score. The 22-day PAS score is significantly associated with only 3 variables: type of surgery, pT, and resection of one arytenoid. From the data presented, the factors that most delay an effective recovery of swallowing are T3 and the resection of one arytenoid. Early decannulation has been shown statistically to improve PAS score in the short term, but not in the long term.

摘要

在环状软骨上部分喉切除术后十天内进行早期拔管,在短期内(约30天)可使吞咽半固体食物的功能恢复得更快。我们选择了20例行环状软骨上喉切除术的喉鳞状细胞癌患者:10例行环舌骨固定术(CHP),10例行环舌会厌固定术(CHEP)。分期为pT2(10例)和pT3(10例)。在术后平均12天和22天时,采用纤维内镜吞咽评估来评估术后吞咽功能。对于次全喉切除术,采用改良的PAS评分(渗透-误吸量表)。拔管在6.7±2.1天之后进行。单因素分析显示,手术类型(CHP或CHEP)、pT、一侧杓状软骨切除以及拔管时间与术后12天的PAS评分显著相关。术后22天的PAS评分仅与三个变量显著相关:手术类型、pT和一侧杓状软骨切除。根据所呈现的数据,最延迟吞咽功能有效恢复的因素是T3和一侧杓状软骨切除。统计学表明,早期拔管在短期内可改善PAS评分,但长期内无此效果。

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本文引用的文献

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Long-term Swallowing Function, Pulmonary Complications, and Quality of Life after Supracricoid Laryngectomy.声门上喉切除术治疗后长期吞咽功能、肺部并发症和生活质量。
Otolaryngol Head Neck Surg. 2019 Aug;161(2):307-314. doi: 10.1177/0194599819835189. Epub 2019 Mar 12.
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Functional outcomes after supracricoid laryngectomy: what do we not know and what do we need to know?环状软骨上喉切除术后的功能结果:我们不知道什么,又需要知道什么?
Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3459-3475. doi: 10.1007/s00405-015-3822-3. Epub 2015 Nov 6.
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Eur Arch Otorhinolaryngol. 2012 Jun;269(6):1635-46. doi: 10.1007/s00405-012-1928-4.
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Otolaryngol Head Neck Surg. 2010 Jun;142(6):873-8. doi: 10.1016/j.otohns.2010.01.035.
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