Yuan Mingwei, Zhang Yan, Wang Kana, Xi Mingrong
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Front Oncol. 2023 Aug 11;13:1244202. doi: 10.3389/fonc.2023.1244202. eCollection 2023.
Cervical adenocarcinoma accounts for 10%-25% of total cases of cervical carcinoma. But in recent years, the incidence of adenocarcinoma has risen both proportionally and absolutely. Clinically, most cervical adenocarcinoma show no symptom or present with abnormal uterine bleeding or vaginal discharge, similar to squamous cell carcinoma. What different about it is that cervical cytological testing demonstrates a high false-negative rate of cervical adenocarcinoma, potentially leading to the failure in detecting in early stage. This report presents two cases both with pelvic masses, and massive ascites served as the initial symptom, which is similar to the clinical symptom of ovarian cancer, but ultimately diagnosed with cervical adenocarcinoma through surgical specimens. There are few literature reports on this situation. Hence, a literature review also has been performed to improve the recognition for cervical adenocarcinoma presenting with pelvic masses and massive ascites, and to avoid misdiagnosis.
宫颈腺癌占宫颈癌总病例的10%-25%。但近年来,腺癌的发病率在比例和绝对值上均有所上升。临床上,大多数宫颈腺癌无症状或表现为子宫异常出血或阴道分泌物异常,与鳞状细胞癌相似。不同的是,宫颈细胞学检查显示宫颈腺癌的假阴性率较高,可能导致早期检测失败。本报告介绍了两例均以盆腔肿块为表现、大量腹水为首发症状的病例,其临床表现与卵巢癌相似,但最终通过手术标本诊断为宫颈腺癌。关于这种情况的文献报道很少。因此,我们还进行了文献综述,以提高对以盆腔肿块和大量腹水为表现的宫颈腺癌的认识,避免误诊。