Harris Ronald, Rosser Morgan, Mehdiratta Nitin, Chowdhurry Anand, Smith Becky, Krishnamoorthy Vijay
Anesthesiology, Duke University School of Medicine, Durham, USA.
Anesthesiology, Duke University Medical Center, Durham, USA.
Cureus. 2023 Jul 26;15(7):e42501. doi: 10.7759/cureus.42501. eCollection 2023 Jul.
Central Line Associated Blood Stream Infections (CLABSI) continue to be a significant complication for hospitalized patients. Hospitals have used various strategies to reduce CLABSI events due to the significant complications and associated costs. In this QI analysis, we examined the impact of a CLABSI reduction quality improvement project within a single ICU at a tertiary care medical center. Absolute CLABSI counts were compared between this ICU and other health system ICUs that did not implement the bundle. A sustained reduction in absolute CLABSI counts to or near zero was observed over 17 months after implementation. ICUs not performing the interventions during this time consistently reported ≥ 2 CLABSI per month. Further analysis is needed to assess causality and the generalizability of bundle components to other ICUs. These findings may provide other health systems with additional strategies to prevent CLABSI and provide consistent, evidence-based supportive care to critically ill patients.
中心静脉导管相关血流感染（CLABSI）仍然是住院患者的一个重大并发症。由于严重的并发症和相关成本，医院已采用各种策略来减少CLABSI事件。在本质量改进分析中，我们研究了在一家三级医疗中心的单一重症监护病房（ICU）内开展的CLABSI减少质量改进项目的影响。将该ICU与未实施集束化干预措施的其他医疗系统ICU的CLABSI绝对计数进行了比较。实施后17个月内观察到CLABSI绝对计数持续减少至零或接近零。在此期间未进行干预的ICU每月持续报告≥2例CLABSI。需要进一步分析以评估因果关系以及集束化干预措施各组成部分对其他ICU的可推广性。这些发现可能为其他医疗系统提供预防CLABSI的额外策略，并为重症患者提供一致的、基于证据的支持性护理。
