Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Adv Tech Stand Neurosurg. 2023;47:225-234. doi: 10.1007/978-3-031-34981-2_8.
Terminal myelocystocele (TMC) has been a puzzling entity of spinal dysraphism. It is found in the sacrococcygeal region usually forming a subcutaneous hump of various sizes. The wide variation of its morphology has been clarified by defining the essential and nonessential features as described in this chapter. Although it is not a common entity, TMC is attractive in that a highly plausible hypothesis on its pathoembryogenesis has been proposed based on observations on the secondary neurulation of the chick embryo. In this chapter, the embryology will be described, followed by the surgical strategy in accordance with the embryogenesis. The clinical features and prognosis will also be presented in detail.
终丝脊髓脊膜膨出（TMC）一直是脊髓发育畸形中一个令人费解的实体。它通常位于骶尾部区域，形成大小不一的皮下肿块。通过定义本章中描述的必要和非必要特征，已经阐明了其形态的广泛变化。尽管 TMC 并不常见，但它很有吸引力，因为根据鸡胚二次神经形成的观察，提出了一个关于其病理胚胎发生的高度合理假说。本章将首先描述胚胎学，然后根据胚胎发生制定手术策略。还将详细介绍临床特征和预后。
