Department of Urology, Seoul National University, College of Medicine, Seoul, Republic of Korea.
Division of Pediatric Urology, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Adv Tech Stand Neurosurg. 2023;47:273-289. doi: 10.1007/978-3-031-34981-2_10.
Micturition requires complex interplay involving bladder, peripheral neural network, spinal cord, and brain. Spinal dysraphism presents variety of neural lesions that may affect this interplay leading to neurogenic bladder. However, the diagnosis of neurogenic bladder in those with spinal dysraphism is often difficult and contrasted to other types of neurogenic bladder caused by complete neural lesions such as spinal cord injury or brain tumor. Typically, neurogenic bladder caused by spinal dysraphism shows lower motor neuron lesion and partial neural injury. However, upper motor signs can be seen with the occurrence of tethered cord syndrome and developmental immaturity of bladder control often complicated by fecal impaction. Thus, the diagnosis of tethered cord syndrome should be made cautiously. Several invasive and noninvasive diagnostic modalities could be applied for accurate diagnosis, preventing renal damage and controlling urinary incontinence. However, it should be borne in mind that no single study is definitive for accurate diagnosis, so it requires careful scrutiny in interpretation. The follow-up scheme of these patients should be determined to detect urological deterioration due to the development of tethered cord syndrome. Since the development of tethered cord syndrome shows diverse nature implicating urological and orthopedic issues, multidisciplinary collaboration is essential for comprehensive care.
排尿需要涉及膀胱、周围神经网络、脊髓和大脑的复杂相互作用。脊髓脊膜膨出表现出多种神经病变,可能会影响这种相互作用,导致神经性膀胱。然而,对于脊髓脊膜膨出患者的神经性膀胱的诊断通常很困难,与其他类型的神经性膀胱(如脊髓损伤或脑肿瘤引起的完全性神经病变)不同。通常,由脊髓脊膜膨出引起的神经性膀胱表现为下运动神经元病变和部分神经损伤。然而,随着脊髓栓系综合征的发生和膀胱控制的发育不成熟,也可以出现上运动神经元体征,常伴有粪便嵌塞。因此,脊髓栓系综合征的诊断应谨慎。可以应用几种有创和无创的诊断方法进行准确诊断,防止肾脏损害和控制尿失禁。然而,应该记住,没有单一的研究可以对准确的诊断具有确定性,因此需要仔细审查解释。应确定这些患者的随访方案,以检测由于脊髓栓系综合征的发展而导致的尿动力学恶化。由于脊髓栓系综合征的发展具有涉及泌尿科和骨科问题的多样性,因此多学科合作对于全面护理至关重要。