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《2023 - 2024年儿童流感防控建议》

Recommendations for Prevention and Control of Influenza in Children, 2023-2024.

出版信息

Pediatrics. 2023 Oct 1;152(4). doi: 10.1542/peds.2023-063772.

Abstract

This statement updates the recommendations of the American Academy of Pediatrics for the routine use of influenza vaccine and antiviral medications in the prevention and treatment of influenza in children during the 2023-2024 influenza season. A detailed review of the evidence supporting these recommendations is published in the accompanying technical report (www.pediatrics.org/cgi/doi/10.1542/peds.2023-063773). The American Academy of Pediatrics recommends annual influenza vaccination of all children without medical contraindications starting at 6 months of age. Children are at risk for hospitalization and death from influenza. Influenza vaccination is an important strategy for protecting children and the broader community, as well as reducing the overall burden of respiratory illnesses when other viruses are cocirculating. Any licensed influenza vaccine appropriate for age and health status can be administered, ideally as soon as possible in the season, without preference for one product or formulation over another. Antiviral treatment of influenza is recommended for children with suspected (eg, influenza-like illness [fever with either cough or sore throat]) or confirmed influenza who are hospitalized, have severe or progressive disease, or have underlying conditions that increase their risk of complications of influenza, regardless of duration of illness. Antiviral treatment should be initiated as soon as possible. Antiviral treatment may be considered in the outpatient setting for symptomatic children with suspected or confirmed influenza disease who are not at high risk for influenza complications, if treatment can be initiated within 48 hours of illness onset. Antiviral treatment may also be considered for children with suspected or confirmed influenza disease whose siblings or household contacts either are younger than 6 months or have a high-risk condition that predisposes them to complications of influenza. Antiviral chemoprophylaxis is recommended for the prevention of influenza virus infection as an adjunct to vaccination in certain individuals, especially exposed children who are at high risk for influenza complications but have not yet been immunized or those who are not expected to mount an effective immune response.

摘要

本声明更新了美国儿科学会关于在2023-2024流感季节预防和治疗儿童流感时常规使用流感疫苗和抗病毒药物的建议。支持这些建议的证据详细综述发表在随附的技术报告中(www.pediatrics.org/cgi/doi/10.1542/peds.2023-063773)。美国儿科学会建议,所有无医学禁忌证的儿童从6个月大开始每年接种流感疫苗。儿童有因流感住院和死亡的风险。接种流感疫苗是保护儿童和更广泛社区的重要策略,同时在其他病毒共同流行时减少呼吸道疾病的总体负担。可接种任何适合年龄和健康状况的已获许可的流感疫苗,理想情况下应在流感季节尽早接种,不偏好某一种产品或剂型优于另一种。对于疑似(如流感样疾病[发热伴咳嗽或咽痛])或确诊流感且住院、患有严重或进展性疾病或有增加流感并发症风险的基础疾病的儿童,无论病程长短,均建议进行流感抗病毒治疗。抗病毒治疗应尽早开始。对于疑似或确诊流感疾病但无流感并发症高风险的有症状门诊儿童,如果能在发病后48小时内开始治疗,可考虑进行抗病毒治疗。对于疑似或确诊流感疾病但其兄弟姐妹或家庭接触者年龄小于6个月或有易患流感并发症的高风险状况的儿童,也可考虑进行抗病毒治疗。对于某些个体,尤其是暴露后有流感并发症高风险但尚未接种疫苗或预计无法产生有效免疫反应的儿童,建议将抗病毒化学预防作为疫苗接种的辅助手段用于预防流感病毒感染。

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