Kent Ali Erman, Gürses Emre, Karabekiroğlu Figen, Genç Aydan
Department of Audiology, Ondokuz Mayıs University, Samsun, Turkey.
Department of Audiology, Hacettepe University Faculty of Health Sciences, Ankara, Turkey.
Curr Rheumatol Rev. 2023 Aug 28. doi: 10.2174/1573397119666230828162611.
Balance weaknesses related to mobility and fall risk in patients with rheumatic diseases are well-known. Vestibular dysfunction could negatively contribute to the balance ability of this patient population. This study aims to investigate the effects of Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS), among the most common rheumatic diseases, on postural balance related to vestibular function.
Seventy-eight participants were grouped as RA (n=34, 43%), AS (n=24, 30.7%), and the control group consisted of healthy individuals (n=20, 25.6%). Cervical Vestibular Evoked Myogenic Potentials (cVEMP) test, which assesses the vestibular function objectively, Dizziness Handicap Inventory (DHI), which evaluates vertigo subjectively, and Berg Balance Scale (BBS) were performed.
Different degrees of VEMP latency prolongations were found in the AS and RA groups. Right, and left ear N1 latencies were significantly longer in the AS group than in RA and control. Right ear P1 latency prolongation was statistically significant in the RA group. Amplitude asymmetry ratio (AAR) was found to be considerably higher in the RA and AS groups than in the control group (p<0.05). The mean BBS score in the AS group was below the fall risk score of 45. A negative statistically significant effect was observed between latency prolongation and BBS in AS groups.
The abnormal VEMP findings in individuals with RA and AS shows inner ear vestibular system dysfunction. This vestibular impairment strictly contributes to their postural imbalance and requires a focused vestibular rehabilitation program for balance treatment.
风湿性疾病患者中与活动能力和跌倒风险相关的平衡能力缺陷是众所周知的。前庭功能障碍可能会对这一患者群体的平衡能力产生负面影响。本研究旨在调查类风湿关节炎(RA)和强直性脊柱炎(AS)这两种最常见的风湿性疾病对与前庭功能相关的姿势平衡的影响。
78名参与者被分为RA组(n = 34,43%)、AS组(n = 24,30.7%),对照组由健康个体组成(n = 20,25.6%)。进行了客观评估前庭功能的颈前庭诱发肌源性电位(cVEMP)测试、主观评估眩晕的头晕残障量表(DHI)以及伯格平衡量表(BBS)。
在AS组和RA组中发现了不同程度的VEMP潜伏期延长。AS组右耳和左耳的N1潜伏期显著长于RA组和对照组。RA组右耳P1潜伏期延长具有统计学意义。发现RA组和AS组的振幅不对称率(AAR)明显高于对照组(p<0.05)。AS组的平均BBS评分低于跌倒风险分数45。在AS组中观察到潜伏期延长与BBS之间存在统计学上的显著负相关。
RA和AS患者的VEMP异常结果表明内耳前庭系统功能障碍。这种前庭损伤对他们的姿势失衡有严重影响,需要针对性的前庭康复计划来进行平衡治疗。