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探讨子宫颈管夹角在预测单胎妊娠早产中的预测作用:一项荟萃分析。

Investigating the predictive role of uterocervical angle in predicting preterm labor in singleton pregnancies: a meta-analysis.

机构信息

Department of Gynecology and Obstetrics, Health Sciences University, Bursa Yüksek Ihtisas Research and Training Hospital, Türkiye.

Department of Biostatistics, Uludağ University, Faculty of Medicine, Bursa, Türkiye.

出版信息

Ginekol Pol. 2023;94(12):990-996. doi: 10.5603/gpl.95194. Epub 2023 Aug 29.

Abstract

OBJECTIVES

In this meta-analysis, we aimedto demonstrate the relationship between uterocervical angle and preterm labor in singleton pregnancies more clearly and reliablywith this meta-analysis.

MATERIAL AND METODS

In this study, we use keywords such as "uterocervical angle," "cervical angle," "angle," "cervix," "cervical," "preterm," and "preterm labour." We searched various databases, including PubMed, MEDLINE, ClinicalKey, Scopus, ScienceDirect, Web of Science, and Google Scholar. The search encompassed the period from January 1, 2010, to December 27, 2020. As a result of the literature review, a total of 585 articles were identified. After the screening and selection process, six studies met the inclusion criteria and were included in the analysis. These six studies were deemed relevant and provided valuable information on the research topic.

RESULTS

When the Egger test (p = 0.020) and Begg test (p = 0.188) were performed, no significant publication bias was found in the studies examined. These statistical tests assess publication bias, and the resulting p-values indicate a low probability of bias in the included studies. Cochran's Q test revealed the presence of heterogeneity among the included studies. Heterogeneity indicates variability in the results beyond what would be expected by chance alone. This finding suggests that the studies may differ in methodologies, populations, or other factors, which could impact the overall results and require further investigation. There was a significant difference between the patient and control groups (p < 0.001). This result provides strong evidence to support the importance of the difference between the two groups compared.

CONCLUSIONS

Based on the findings of this study, a wider uterocervical angle appeared to be significantly associated with an increased risk of preterm delivery in overall effect. It concluded that a wide uterocervical angle may be a potential risk factor for preterm delivery. Moreover, the study revealed a significant association between wider uterocervical angles and an elevated risk of preterm labour in singleton pregnancies. In this study, the definition of preterm birth accepts as birth before 37 weeks of gestation. These results highlight the potential significance of evaluating the uterocervical angle as a meaningful predictor for identifying the propensity of preterm labour in singleton pregnancies.

摘要

目的

在这项荟萃分析中,我们旨在通过这项荟萃分析更清楚、更可靠地展示单胎妊娠中子宫颈角与早产之间的关系。

材料和方法

在这项研究中,我们使用了“子宫颈角”、“宫颈角”、“角”、“宫颈”、“宫颈”、“早产”和“早产劳动”等关键词。我们搜索了各种数据库,包括 PubMed、MEDLINE、ClinicalKey、Scopus、ScienceDirect、Web of Science 和 Google Scholar。文献检索的时间范围为 2010 年 1 月 1 日至 2020 年 12 月 27 日。通过文献回顾,共确定了 585 篇文章。经过筛选和选择过程,符合纳入标准的共有 6 项研究纳入分析。这些六项研究被认为是相关的,并提供了关于研究主题的有价值的信息。

结果

当进行 Egger 检验(p = 0.020)和 Begg 检验(p = 0.188)时,检查的研究中未发现显著的发表偏倚。这些统计检验评估发表偏倚,得出的 p 值表示纳入研究中存在偏倚的可能性较低。Cochran's Q 检验显示纳入研究存在异质性。异质性表明结果存在超出仅由机会引起的差异。这一发现表明,研究可能在方法学、人群或其他因素方面存在差异,这可能会影响总体结果,需要进一步研究。患者组和对照组之间存在显著差异(p < 0.001)。这一结果提供了有力的证据支持两组之间差异的重要性。

结论

基于这项研究的结果,较大的子宫颈角似乎与总体效应中早产的风险增加显著相关。研究结果表明,较大的子宫颈角可能是早产的潜在危险因素。此外,研究还显示,子宫颈角增宽与单胎妊娠中早产的风险增加之间存在显著关联。在这项研究中,早产的定义接受为 37 周妊娠前分娩。这些结果强调了评估子宫颈角作为识别单胎妊娠早产倾向的有意义预测指标的潜力。

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