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白藜芦醇对葡萄糖代谢影响的综合综述:揭示其在糖尿病管理中的分子途径和治疗潜力。

A comprehensive review of the effects of resveratrol on glucose metabolism: unveiling the molecular pathways and therapeutic potential in diabetes management.

机构信息

Department of Biology Education, Daegu University, 201, Daegudae-ro, Gyeongsan-si, 38453, Gyeongsangbuk-do, Republic of Korea.

出版信息

Mol Biol Rep. 2023 Oct;50(10):8743-8755. doi: 10.1007/s11033-023-08746-1. Epub 2023 Aug 29.

Abstract

Resveratrol, a naturally occurring polyphenolic compound predominantly found in red wine and grapes, has garnered attention for its potential role in regulating carbohydrate digestion, glucose absorption, and metabolism. This review aims to deliver a comprehensive analysis of the molecular mechanisms and therapeutic potential of resveratrol in influencing vital processes in glucose homeostasis. These processes include carbohydrate digestion, glucose absorption, glycogen storage, insulin secretion, glucose metabolism in muscle cells, and triglyceride synthesis in adipocytes.The goal of this review is to offer an in-depth understanding of the multifaceted effects of resveratrol on glucose metabolism. By doing so, it presents valuable insights into its potential applications for preventing and treating metabolic disorders. This comprehensive examination of resveratrol's impact on glucose management will contribute to the growing body of knowledge on this promising natural compound, which may benefit researchers, healthcare professionals, and individuals interested in metabolic disorder prevention and treatment.

摘要

白藜芦醇是一种天然存在的多酚化合物,主要存在于红酒和葡萄中,因其在调节碳水化合物消化、葡萄糖吸收和代谢方面的潜在作用而受到关注。本综述旨在全面分析白藜芦醇影响葡萄糖稳态重要过程的分子机制和治疗潜力。这些过程包括碳水化合物消化、葡萄糖吸收、糖原储存、胰岛素分泌、肌细胞葡萄糖代谢和脂肪细胞甘油三酯合成。本综述的目的是深入了解白藜芦醇对葡萄糖代谢的多方面影响。通过这样做,它为其在预防和治疗代谢紊乱方面的潜在应用提供了有价值的见解。本综述对白藜芦醇对葡萄糖管理影响的全面考察将有助于丰富人们对白藜芦醇这一有前途的天然化合物的认识,这可能使研究人员、医疗保健专业人员和关注代谢紊乱预防和治疗的个人受益。

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