Hoang-Ngoc M, Smadja A, Pietri J, Garnier T
Rev Fr Gynecol Obstet. 1986 Jun-Jul;81(6-7):341-4.
Carcinomatous degeneration of the endometrium is rarely seen. The authors consider the pathogenesis of this disorder based on two authentic cases. On the basis of their previous studies of the endometrium, the authors suggest that endometriotic centers are simply "dystrophies" developing from subcoelomic mesenchymal cells which although quiescent are still capable of proliferation and differentiation. "Dystrophies" are insensitive to hormonal incitation and this would explain the rarity of carcinomatous degeneration of the endometrium.
子宫内膜的癌性退变很少见。作者基于两例真实病例探讨了这种病症的发病机制。基于他们之前对子宫内膜的研究，作者认为子宫内膜异位中心仅仅是由体腔下间充质细胞发展而来的“营养不良性病变”，这些细胞虽然处于静止状态，但仍有增殖和分化的能力。“营养不良性病变”对激素刺激不敏感，这就解释了子宫内膜癌性退变罕见的原因。
