Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan.
Department of Ophthalmology, Evangelical Hospital of Belo Horizonte, Belo Horizonte, Brazil; and.
Retin Cases Brief Rep. 2023 Sep 1;17(5):577-580. doi: 10.1097/ICB.0000000000001243.
To report a case of epiretinal crystalline deposits observed on fundus examination and optical coherence tomography 2 years after transzonular intravitreal injection of triamcinolone-moxifloxacin (TriMoxi) during "dropless" cataract surgery.
Observational case report with literature review of toxic effects of intravitreal triamcinolone and differential diagnosis of retinal crystalline deposits.
A 37-year-old asymptomatic pseudophakic man presented with refractile crystalline retinal deposits that had prompted an extensive systemic embolic workup. The systemic evaluation for emboli was negative. OCT imaging revealed that the crystalline deposits were confined to the anterior surface of the internal limiting membrane. Further historical inquiry determined that transzonular intravitreal triamcinolone-moxifloxacin injection had been performed at the time of cataract surgery 2 years earlier.
Transzonular triamcinolone acetonide delivered during cataract surgery can deposit on the retinal surface for long periods. These epiretinal crystalline deposits are benign and generally do not interfere with visual acuity. Nevertheless, clinicians should be aware of this differential diagnosis because clinical misdiagnosis can lead to unwarranted evaluation and treatment.
报告一例在“无滴”白内障手术后经巩膜隧道内玻璃体内注射曲安奈德-莫西沙星(TriMoxi) 2 年后,眼底检查和光相干断层扫描(OCT)发现的后视网膜晶体状沉积物病例。
对眼内注射曲安奈德的毒性作用及视网膜晶体状沉积物的鉴别诊断进行观察性病例报告和文献复习。
一名 37 岁的无症状人工晶状体眼男性出现反射性晶体状视网膜沉积物,这促使进行了广泛的全身性栓塞性检查。全身性栓塞检查结果为阴性。OCT 成像显示晶体沉积物局限于内界膜的前表面。进一步的病史询问确定,在 2 年前的白内障手术时进行了巩膜隧道内玻璃体内曲安奈德-莫西沙星注射。
在白内障手术期间经巩膜隧道内注射的曲安奈德可以在视网膜表面长时间沉积。这些后视网膜晶体状沉积物是良性的,通常不会影响视力。然而,临床医生应该了解这种鉴别诊断,因为临床误诊可能导致不必要的评估和治疗。