Rahman Md Atikur, Venkataram Tejas, Habib Riad, Jahan Nwoshin, Raihan Farid, Alam Shamsul, Mahmood Ehsan, Umana Giuseppe E, Chaurasia Bipin
Department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Shahbag, Bangladesh.
Department of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.
J Korean Neurosurg Soc. 2024 Jan;67(1):122-129. doi: 10.3340/jkns.2022.0273. Epub 2023 Aug 30.
Paragangliomas are rare neuroendocrine tumors that are usually benign in nature. They may be either familial or sporadic in their occurrence. Numerous neuroendocrine tumors are collectively included under the umbrella of paragangliomas. Among them, carotid body tumors and glomus jugulare tumors are extremely rare. Thus, we present a rare case of 29-year-old male who was admitted with hearing difficulties and tinnitus in the left ear, with swelling on the left side of the neck. Based on clinical and radiological findings, a diagnosis of left-sided glomus jugulare with carotid body tumor was made. The patient underwent a twostage surgery with an interval of approximately 2 months. Histopathology revealed a paraganglioma. Herein, we present the clinical features, imaging findings, management, and a brief review of literature on the classification, evaluation, and management of carotid body and glomus jugulare tumors. Paraganglioma is a slow-growing tumor. The synchronous occurrence of carotid body and glomus jugulare tumors is infrequent. Microsurgical resection remains the primary treatment modality. Therefore, our patient underwent two-stage surgery. The rarity of occurrence and the proximity and adherence to vital neurovascular structures have resulted in the treatment of paragangliomas remaining a challenge.
副神经节瘤是一种罕见的神经内分泌肿瘤,通常为良性。其发生可能为家族性或散发性。众多神经内分泌肿瘤都被统称为副神经节瘤。其中,颈动脉体瘤和颈静脉球瘤极为罕见。因此,我们报告一例罕见病例,一名29岁男性因左耳听力困难和耳鸣入院,伴有左侧颈部肿胀。根据临床和影像学检查结果,诊断为左侧颈静脉球瘤合并颈动脉体瘤。该患者接受了间隔约2个月的两期手术。组织病理学显示为副神经节瘤。在此,我们介绍其临床特征、影像学表现、治疗方法,并对颈动脉体瘤和颈静脉球瘤的分类、评估及治疗的相关文献进行简要综述。副神经节瘤是一种生长缓慢的肿瘤。颈动脉体瘤和颈静脉球瘤同时发生的情况并不常见。显微手术切除仍然是主要的治疗方式。因此,我们的患者接受了两期手术。副神经节瘤发生的罕见性以及与重要神经血管结构的接近和粘连,使得其治疗仍然是一项挑战。