Hoffmann R, Germann E J, Schmidt U, Jenss H
Schweiz Med Wochenschr. 1986 Aug 16;116(33):1098-102.
Primary biliary cirrhosis was diagnosed in a 48-year-old woman in the light of clinical and laboratory data, antimitochondrial antibodies and histologic features in liver biopsy. Four years later the patient developed pulmonary infiltration of changing localization. Histologic investigation of transbronchial biopsy revealed granulomas in the bronchial mucosa and peribronchial tissue. There were no further signs of sarcoidosis. The question is discussed whether granulomatous pulmonary infiltrations are an extrahepatic manifestation of primary biliary cirrhosis.
根据临床和实验室数据、抗线粒体抗体以及肝活检的组织学特征,一名48岁女性被诊断为原发性胆汁性肝硬化。四年后,该患者出现了肺部浸润,部位不断变化。经支气管活检的组织学检查显示支气管黏膜和支气管周围组织中有肉芽肿。没有结节病的进一步迹象。本文讨论了肉芽肿性肺部浸润是否为原发性胆汁性肝硬化的肝外表现这一问题。