Schamaun M, Rüttimann A
Schweiz Med Wochenschr. 1986 Sep 13;116(37):1249-52.
In thoracic surgery patients the etiology of cavities has drastically changed in the last 20 years. While at present only very few patients need surgery for cavernous tuberculosis, cavities of cancerous origin are becoming more and more frequent. During the period from 1977 to 1985 24 out of 225 bronchogenic carcinomas treated by resection were found to be cavernous (10.7%). Radiologically the degree of cavitation extended from a small marginal or central air collection to the formation of large, irregular, and thick-walled caverns. The excavation is the result of necrobiotic changes within the tumor. It arises when the tumor masses penetrate into the bronchial tree and are expectorated. However, prognosis of cavitated cancer remains exclusively dependent on the stage of the tumor. The cavitation itself seems not to influence it.
在过去20年里，胸外科手术患者中空洞形成的病因已发生了巨大变化。目前，仅有极少数患者因海绵状肺结核需要手术，而癌源性空洞却越来越常见。在1977年至1985年期间，接受切除治疗的225例支气管源性癌中，有24例发现有空洞形成（10.7%）。放射学上，空洞程度从微小的边缘或中央气体聚集到形成大的、不规则的厚壁空洞不等。空洞形成是肿瘤内部坏死性改变的结果。当肿瘤团块侵入支气管树并咳出时就会出现空洞。然而，有空洞的癌症的预后完全取决于肿瘤的分期。空洞本身似乎并不影响预后。
