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Dexamethasone palmitate as an etoposide-free treatment for children with hemophagocytic lymphohistiocytosis after hematopoietic cell transplantation.

作者信息

Ono Rintaro, Sakamoto Kenichi, Doi Takehiko, Yanagisawa Ryu, Morimoto Akira, Kanegane Hirokazu, Nakazawa Yozo, Shioda Yoko

机构信息

Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.

Department of Pediatrics, Shiga University of Medical Science, Shiga, Japan.

出版信息

Bone Marrow Transplant. 2023 Nov;58(11):1286-1288. doi: 10.1038/s41409-023-02098-x. Epub 2023 Aug 29.

DOI:10.1038/s41409-023-02098-x
PMID:37644136
Abstract
摘要

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Int J Hematol. 2025 Feb;121(2):252-256. doi: 10.1007/s12185-024-03892-z. Epub 2024 Dec 4.

本文引用的文献

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Haemophagocytic lymphohistiocytosis (HLH) following allogeneic haematopoietic stem cell transplantation (HSCT)-time to reappraise with modern diagnostic and treatment strategies?异基因造血干细胞移植（HSCT）后噬血细胞性淋巴组织细胞增生症（HLH）——是时候用现代诊断和治疗策略重新评估了吗？
Bone Marrow Transplant. 2020 Feb;55(2):307-316. doi: 10.1038/s41409-019-0637-7. Epub 2019 Aug 27.
2
Macrophage elimination in bone marrow by dexamethasone palmitate is associated with successful engraftment in patients with hemophagocytic syndrome.棕榈酸地塞米松对骨髓中巨噬细胞的清除作用与噬血细胞综合征患者的成功植入相关。
Int J Hematol. 2019 Aug;110(2):260-262. doi: 10.1007/s12185-019-02659-1. Epub 2019 May 16.
3
Hypercytokinemia with hemophagocytic syndrome due to human metapneumovirus.
Pediatr Int. 2018 Oct;60(10):974-976. doi: 10.1111/ped.13665.
4
Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study.依托泊苷和地塞米松治疗噬血细胞性淋巴组织细胞增生症的确证疗效：HLH - 2004合作研究的长期结果
Blood. 2017 Dec 21;130(25):2728-2738. doi: 10.1182/blood-2017-06-788349. Epub 2017 Sep 21.
5
Dexamethasone palmitate for patients with engraftment syndrome is associated with favorable outcome for children with hematological malignancy.棕榈酸地塞米松用于植入综合征患者对血液系统恶性肿瘤患儿的预后有益。
Bone Marrow Transplant. 2016 Nov;51(11):1540-1542. doi: 10.1038/bmt.2016.178. Epub 2016 Jul 4.
6
Hemophagocytic lymphohistiocytosis caused by systemic herpes simplex virus type 1 infection: Successful treatment with dexamethasone palmitate.1型全身性单纯疱疹病毒感染引起的噬血细胞性淋巴组织细胞增生症：棕榈酸地塞米松成功治疗
Pediatr Int. 2016 May;58(5):390-393. doi: 10.1111/ped.12817. Epub 2016 Apr 14.
7
Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation: macrophage-targeted steroid therapy.棕榈酸地塞米松成功减轻异基因干细胞移植后噬血细胞综合征：巨噬细胞靶向类固醇治疗。
Int J Hematol. 2012 Apr;95(4):428-33. doi: 10.1007/s12185-012-1023-z. Epub 2012 Feb 15.
8
Hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation in children: a nationwide survey in Japan.儿童造血干细胞移植后噬血细胞性淋巴组织细胞增生症：日本全国性调查。
Pediatr Blood Cancer. 2012 Jul 15;59(1):110-4. doi: 10.1002/pbc.23384. Epub 2011 Oct 28.
9
Encouraging results of low-dose etoposide in the treatment of early-onset hemophagocytic syndrome following allogeneic hematopoietic stem cell transplantation.低剂量依托泊苷治疗异基因造血干细胞移植后早发型噬血细胞综合征的鼓舞人心的结果。
Int J Hematol. 2007 Dec;86(5):466-7. doi: 10.1007/BF02984009.
10
Successful treatment with liposteroid followed by reduced intensity stem cell transplantation in an infant with perforin deficiency presenting with hemophagocytic lymphohistiocytosis.一名患有穿孔素缺乏症并表现为噬血细胞性淋巴组织细胞增生症的婴儿，在接受脂类固醇成功治疗后进行了低强度干细胞移植。
J Pediatr Hematol Oncol. 2007 Mar;29(3):178-82. doi: 10.1097/MPH.0b013e3180335030.