Patrone Lorenzo, Ysa August, Covani Marco, Lichaa Hady
West London Vascular and Interventional Centre, Northwick Park Hospital, Harrow, UK.
Department of Vascular Surgery, Hospital Universitario Cruces, Barakaldo, Spain.
J Endovasc Ther. 2025 Jun;32(3):616-626. doi: 10.1177/15266028231195538. Epub 2023 Aug 30.
One of the main skillsets required to tackle endovascular revascularization of complex peripheral chronic total occlusions (CTOs) is wire crossing into the distal true lumen. There are a lot of factors that influence the use of specific catheter and wire strategies, and these include vessel calcification, occlusion length, previous stents, vessel reconstitution zone, availability of retrograde access, operator experience, and available equipment of the shelf. More than the last 2 decades, various dedicated CTO devices have been developed to meet these specific clinical needs; however, their widespread use has been limited by the lack of availability around the world and considerable cost. Hence, the ability to cross complex lesions with the use of widely available simple catheters and wires is crucial for effective limb salvage in this significantly undertreated patient population. The customization of specific techniques to treat individual patients and anatomical subsets is one of the most creative and innovative aspects of the endovascular revascularization field.Clinical ImpactInfra-inguinal Chronic Total Occlusions recanalisation is considered technically challenging. The conventional manipulation of standard guidewires and catheters has proven to be successful in a considerable percentage of cases but success rate could dramatically drop in presence of challenging lesions. The additional use of retrograde access and re-entry devices could increase technical success but could negatively affect procedural time and overall costs. Twenty different techniques of Chronic Total Occlusions antegrade crossing are hereby described with appropriate schematic representations. The aim is to help operators to apply them in specific anatomy subsets and clinical presentations and ultimately to increase procedural success rate.
处理复杂外周慢性完全闭塞病变(CTO)的血管腔内再血管化所需的主要技能之一是将导丝穿过至远端真腔。有许多因素会影响特定导管和导丝策略的使用,这些因素包括血管钙化、闭塞长度、既往支架情况、血管重建区、逆行入路的可用性、术者经验以及现有可用设备。在过去20多年里,已经研发了各种专门用于CTO的器械以满足这些特定临床需求;然而,它们的广泛应用受到全球范围内供应不足和成本高昂的限制。因此,利用广泛可用的简单导管和导丝穿过复杂病变的能力对于挽救这类治疗严重不足的患者肢体至关重要。针对个体患者和解剖亚组定制特定技术是血管腔内再血管化领域最具创造性和创新性的方面之一。
临床影响
腹股沟下慢性完全闭塞病变的再通在技术上具有挑战性。标准导丝和导管的传统操作在相当比例的病例中已被证明是成功的,但在存在具有挑战性的病变时成功率可能会大幅下降。额外使用逆行入路和再入装置可能会提高技术成功率,但可能会对手术时间和总体成本产生负面影响。本文通过适当的示意图描述了20种慢性完全闭塞病变正向穿过的不同技术。目的是帮助术者在特定的解剖亚组和临床表现中应用这些技术,最终提高手术成功率。