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口腔舌癌 192铱植入治疗中总剂量-剂量率关系的统计学评估

Statistical evaluation of a total dose-dose rate relationship in oral tongue cancer 192 Ir implants.

作者信息

Feroldi P, Frata P, Baroncelli G, Belletti S

出版信息

Strahlenther Onkol. 1986 Sep;162(9):561-4.

PMID:3764680
Abstract

A statistical tool has been made by us on 55 patients treated for oral tongue cancer with unique 192 Ir interstitial curietherapy in Brescia from 1973 to 1981. Our aim was to verify a simple analytical relationship proposed and adopted by us for oral tongue cancer implants in order to reduce the total dose with increasing dose rates and to calculate the equivalent total dose when referred to 0.357 Gy/hr. Recurrences and radionecroses are studied in a variance analysis, distinguishing according to stage and total dose; within the dose rate range used, a highly significant difference in radionecrosis rate (P less than 0.005) confirms our isoeffect relationship.

摘要

我们针对1973年至1981年在布雷西亚接受独特的192铱间质近距离放射治疗的55例口腔舌癌患者制作了一种统计工具。我们的目的是验证我们提出并采用的用于口腔舌癌植入的简单分析关系,以便随着剂量率增加降低总剂量,并计算参考0.357 Gy/小时的等效总剂量。在方差分析中研究复发和放射性坏死,根据分期和总剂量进行区分;在所使用的剂量率范围内,放射性坏死率存在高度显著差异(P小于0.005),证实了我们的等效应关系。

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