Iurenov A P, Kozdoba O A, Vikhert A M, Lediashova G A, Erina E V
Ter Arkh. 1986;58(6):128-32.
The nature of a course of "mild" arterial hypertension was studied in 126 patients for 8-10 yrs. It was shown that in 13.2% of the cases arterial pressure returned to normal values during a "natural" course of disease; border-line arterial hypertension was revealed in 9.4%. Stage II hypertension was diagnosed in 77.4% of the cases after 7-10 yrs. Progression of arterial hypertension was noted in this group in 1/3 of the cases (30.2%). Aggravated heredity and an initial morphological state of the kidneys (according to the results of intravital morphological investigation) were shown to be predictors of prognosis of arterial hypertension. The initial picture of the fundus of the eye and electrocardiographic signs of myocardial hypertrophy reflected the nature of a course of hypertension being not factors determining prognosis of arterial hypertension stabilization.
对126例患者的“轻度”动脉高血压病程进行了8至10年的研究。结果显示,在疾病的“自然”病程中,13.2%的病例血压恢复正常;9.4%的病例显示为临界动脉高血压。7至10年后,77.4%的病例被诊断为II期高血压。该组中有1/3的病例(30.2%)出现动脉高血压进展。遗传因素加重以及肾脏的初始形态状态(根据活体形态学检查结果)被证明是动脉高血压预后的预测指标。眼底的初始表现和心肌肥厚的心电图体征反映了高血压病程的性质,但并非决定动脉高血压稳定预后的因素。