University Centre for Research and Development, Chandigarh University, Mohali, India.
Department of Chemistry, Chandigarh University, Mohali, India.
Crit Rev Anal Chem. 2024;54(8):3428-3452. doi: 10.1080/10408347.2023.2250876. Epub 2023 Aug 30.
As a commonly well-known industrial chemical, phthalates are produced in high volumes to be used in various consumer products (e.g., plasticizers, medical devices, construction materials, and toys) to enhance softness, durability, transparency, and flexibility. Phthalates are generally not chemically bonded to the polymer chain of the plastic in which they are mixed. Thus, they may leach, migrate, or evaporate into indoor/outdoor air, and foodstuffs. In this review, a comprehensive overview of several sample preparation methods coupled with gas chromatography for the analysis of phthalates in various kinds of complex matrices, with a focus on the last 20 years' worth of papers. The review begins by highlighting the environmental significance of phthalate pollution along with the various routes to their exposure to general population. Then, the discussion is extended to cover the pretreatment and extraction techniques for phthalates for their quantitation based on gas chromatographic approach. Finally, the present and future challenges for the detection of phthalates in aqueous and food matrices are discussed.
作为一种常见的工业化学品，邻苯二甲酸酯的产量很高，用于各种消费品（如增塑剂、医疗器械、建筑材料和玩具）中，以提高柔软度、耐久性、透明度和灵活性。邻苯二甲酸酯通常不会与聚合物链发生化学结合。因此，它们可能会渗出、迁移或蒸发到室内/室外空气中，以及食物中。在这篇综述中，我们全面概述了几种与气相色谱法相结合的样品制备方法，用于分析各种复杂基质中的邻苯二甲酸酯，重点介绍了过去 20 年的研究论文。综述首先强调了邻苯二甲酸酯污染的环境意义以及普通人群接触邻苯二甲酸酯的各种途径。然后，讨论扩展到涵盖基于气相色谱法的邻苯二甲酸酯定量分析的预处理和提取技术。最后，讨论了目前和未来在水和食品基质中检测邻苯二甲酸酯的挑战。
