Riabov S I, Plotkin V Ia, Klemina I K
Ter Arkh. 1986;58(8):65-71.
The authors provide the clinico-morphological data obtained in 189 patients with primary glomerulonephritis (GN). The disease was manifested clinically by the nephrotic syndrome (NS). The NS was most commonly induced by membranous-proliferative GN (MPGN), membranous GN (MGN), diffuse mesangio-proliferative GN and focal segmental glomerulosclerosis (FSGS), accounting for 31, 25, 22.8 and 8.7% of cases, respectively. Hypertension together with edema was among the most common symptoms of the NS in adult patients. Functional disorders of the kidneys recorded in FSGS, MPGN and MGN patients were more significant as compared to those in other patients. The morphological findings alone, obtained with the aid of light, immunofluorescent and electron microscopy, play the key role in the diagnosis of different patterns of GN.
作者提供了189例原发性肾小球肾炎（GN）患者的临床形态学数据。该疾病临床上表现为肾病综合征（NS）。NS最常见由膜增生性肾小球肾炎（MPGN）、膜性肾小球肾炎（MGN）、弥漫性系膜增生性肾小球肾炎和局灶节段性肾小球硬化症（FSGS）引起，分别占病例的31%、25%、22.8%和8.7%。高血压伴水肿是成年患者NS最常见的症状之一。与其他患者相比，FSGS、MPGN和MGN患者记录的肾脏功能障碍更为显著。仅通过光镜、免疫荧光和电子显微镜获得的形态学发现，在不同类型GN的诊断中起关键作用。
