Tikhonov V P, Bol'shakova R Kh
Ter Arkh. 1986;58(8):73-6.
Ischemic renal lesion in 108 patients with hypertension was diagnosed by means of the determination of slow isoenzymes of carbonic esterases (CE5-7) in the urine. Their detection was a poor prognostic sign for any therapeutic method, particularly with the use of propranolol deteriorating renal circulation. The use of drugs not deteriorating or improving the renal blood flow (dopegyt, chlophelin, reserpine, apressin, corinfar, isoptin) brought about more promising results in such cases.
通过测定108例高血压患者尿液中碳酸酯酶的慢速同工酶（CE5 - 7），诊断出缺血性肾损害。对于任何治疗方法而言，检测到这些同工酶都是不良预后指标，尤其是使用普萘洛尔会使肾循环恶化。在这类病例中，使用不恶化或改善肾血流量的药物（多匹吉、氯非宁、利血平、垂体后叶素、冠心宁、异搏定）能带来更有希望的结果。
