Al-Janabi Moatasem Hussein, Hussein Bayan Youssef Alsayed, Kahwaji Julia Nehad, Haidar Maen, Mortada Aiman, Salloum Rabab
Department of Pathology, Cancer Research Center, Tishreen University Hospital, Latakia, Syria.
Tishreen University Faculty of Medicine, Latakia, Syria.
Int J Surg Case Rep. 2023 Sep;110:108714. doi: 10.1016/j.ijscr.2023.108714. Epub 2023 Aug 23.
Eosinophilic cholecystitis is an unusual condition in which more than 90 % of the inflammatory infiltrate in the gallbladder wall is comprised of eosinophils. The pathogenesis of eosinophilic cholecystitis is still unknown, but in some cases, it is related to hyper-eosinophilic syndrome, parasitosis, infections, and drugs.
We described two cases in which a woman aged 27 years and a man aged 30 years presented with acute and chronic cholecystitis symptoms, respectively. The ultrasound revealed calculous cholecystitis. The cholecystectomy was performed, and the pathological examination of the surgical specimen revealed eosinophilic cholecystitis.
Eosinophilic cholecystitis is a rare disease of the gallbladder. It accounts for 0.25 to 6.4 % of cholecystitis cases. It is characterized by eosinophils infiltration in the lamina propria and the muscle layer. There are no specific symptoms of this disease; it presents as typical cholecystitis. The histopathological investigation is the gold standard for diagnosing eosinophilic cholecystitis, and cholecystectomy is the ultimate treatment for it.
Eosinophilic cholecystitis is a rare condition characterized by acute cholecystitis with eosinophilic infiltration of the gallbladder. In patients with eosinophilic cholecystitis, a comprehensive assessment of the underlying causes is recommended.
嗜酸性粒细胞性胆囊炎是一种罕见病症，其中胆囊壁中超过90%的炎性浸润由嗜酸性粒细胞组成。嗜酸性粒细胞性胆囊炎的发病机制尚不清楚，但在某些情况下，它与高嗜酸性粒细胞综合征、寄生虫病、感染及药物有关。
我们描述了两例病例，分别为一名27岁女性和一名30岁男性，前者表现为急性胆囊炎症状，后者表现为慢性胆囊炎症状。超声检查显示为结石性胆囊炎。实施了胆囊切除术，手术标本的病理检查显示为嗜酸性粒细胞性胆囊炎。
嗜酸性粒细胞性胆囊炎是一种罕见的胆囊疾病。它占胆囊炎病例的0.25%至6.4%。其特征是固有层和肌层有嗜酸性粒细胞浸润。该疾病无特异性症状；表现为典型的胆囊炎。组织病理学检查是诊断嗜酸性粒细胞性胆囊炎的金标准，胆囊切除术是其最终治疗方法。
嗜酸性粒细胞性胆囊炎是一种罕见病症，其特征为急性胆囊炎伴胆囊嗜酸性粒细胞浸润。对于嗜酸性粒细胞性胆囊炎患者，建议对潜在病因进行全面评估。
