Ruige P, van Oostrom C
Tijdschr Kindergeneeskd. 1986 Aug;54(4):107-11.
Bleeding tendency in Noonan-patients is only sporadically mentioned in literature. There is no equivocal opinion about its cause. By means of a questionnaire data were collected from 29 Noonan-patients, registered in our hospital. In about half of these patients these data indicated the existence of a bleeding tendency. Some of these patients revealed a marked thrombocytopathy characterised as a disturbance in secondary aggregation. Further research into the cause is desirable.
努南综合征患者的出血倾向在文献中仅偶尔被提及。对于其病因尚无明确的观点。通过问卷调查，我们收集了我院登记的29例努南综合征患者的数据。在大约一半的这些患者中，这些数据表明存在出血倾向。其中一些患者表现出明显的血小板病，其特征为继发性聚集障碍。有必要对病因进行进一步研究。
