Zhang L J, Lu G M
Department of Radiology, General Hospital of Eastern Theater Command, Nanjing 210016, China.
Zhonghua Yi Xue Za Zhi. 2023 Sep 5;103(33):2543-2545. doi: 10.3760/cma.j.cn112137-20221214-02643.
PET/MRI integrates anatomical, functional and metabolic information, and is increasingly used in the field of clinical oncology, including early diagnosis of disease, local staging, detection of systemic metastases, evaluation of treatment efficacy and prognosis. In addition to fine anatomical structure, MRI multiparametric imaging can also provide functional information of the lesion. Combined with metabolic information of PET, MRI multiparametric imaging can better evaluate the benign and maligant lesions, tumor grade and extent of invasion, and identify tumor recurrence and radiation necrosis. The development of new PET tracers, optimization of MRI sequences and examination paths, combined with high-throughput image quantitative analysis methods, radiomics, artificial intelligence and other new technologies will further promote the application of PET/MRI in oncology.
PET/MRI整合了解剖、功能和代谢信息，越来越多地应用于临床肿瘤学领域，包括疾病的早期诊断、局部分期、全身转移灶的检测、治疗疗效评估和预后判断。除了精细的解剖结构外，MRI多参数成像还能提供病变的功能信息。结合PET的代谢信息，MRI多参数成像能更好地评估病变的良恶性、肿瘤分级和侵袭范围，识别肿瘤复发和放射性坏死。新型PET示踪剂的研发、MRI序列及检查路径的优化，结合高通量图像定量分析方法、放射组学、人工智能等新技术，将进一步推动PET/MRI在肿瘤学中的应用。
