Voirol-Perrin Julia, Stamm Gian-Marco, Salvador Nunes Luis, Schoepfer Alain
Service de gastroentérologie et d'hépatologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Rev Med Suisse. 2023 Aug 30;19(839):1554-1557. doi: 10.53738/REVMED.2023.19.839.1554.
Functional dyspepsia is defined by epigastric pain/burning, postprandial fullness and/or early satiety that have been present for at least six months before diagnosis, including three consecutive months, without evidence of an organic cause likely to explain these symptoms. The pathogenesis is complex and incompletely understood. The initial assessment includes a thorough history, physical examination, blood work, celiac disease serology and ruling out Helicobacter pylori infection. Most patients will undergo upper gastrointestinal endoscopy and abdominal ultrasound to exclude organic differential diagnoses. The therapy is multi-facetted and includes, among others, proton pump inhibitors, Helicobacter pylori eradication, herbal agents, and neuromodulators.
功能性消化不良的定义为上腹部疼痛/烧灼感、餐后饱胀和/或早饱感，这些症状在诊断前已出现至少六个月，包括连续三个月，且无可能解释这些症状的器质性病因证据。其发病机制复杂且尚未完全明确。初始评估包括详细的病史、体格检查、血液检查、乳糜泻血清学检查以及排除幽门螺杆菌感染。大多数患者将接受上消化道内镜检查和腹部超声检查以排除器质性鉴别诊断。治疗是多方面的，包括质子泵抑制剂、根除幽门螺杆菌、草药制剂和神经调节剂等。
