Section of Anaesthesiology and Intensive Care, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Paediatr Anaesth. 2024 Jan;34(1):13-18. doi: 10.1111/pan.14752. Epub 2023 Aug 31.
Since the introduction of Fascial Plane Blocks in 2007 there has been an enormous interest and application of Fascial Plane Blocks, evidenced by substantially more than 1000 PubMed items. Despite this gigantic number of publications, also including randomized controlled trials and meta-analyses in children, there is still no clear-cut insight into how much of the purported effect is in fact due to the blockade of nerve structures and how much is merely adding the well-known analgesic and anti-inflammatory effects of the plasma levels of local anesthetics that are achieved with these techniques. Furthermore, Fascial Plane Blocks appear useful only if compared to conventional multi-modal analgesia (no block or placebo) and Fascial Plane Blocks lack the potency to provide surgical anesthesia on their own and appear only to be of value when used for minor-moderate surgery. Despite the huge literature, there has so far not emerged any clinical situations where Fascial Plane Blocks have definitively been shown to be the block of choice, being decisively more effective than other established regional blocks. Lastly, Fascial Plane Blocks may appear as virtually free of complications, but case reports are emerging that point to a real risk for causing local anesthetic systemic toxicity when using Fascial Plane Blocks. This text aims to synthesize the current knowledge base regarding the Fascial Plane Blocks that are relevant to use in the pediatric context. In summary, there does currently not exist any convincing scientific evidence for the continued support for the use of Fascial Plane Blocks in children, except for the rectus sheath block and possibly also the transmuscular quadratus lumborum block.
自 2007 年 fascial plane blocks(筋膜平面阻滞)问世以来,人们对其产生了浓厚的兴趣并广泛应用,这一点可以从超过 1000 篇 PubMed 文章中得到证明。尽管发表了如此多的文章,包括在儿童中进行的随机对照试验和荟萃分析,但对于所谓的效果有多少实际上是由于神经结构的阻断,以及有多少仅仅是由于这些技术达到的局部麻醉剂血浆水平的已知镇痛和抗炎作用,仍然没有明确的认识。此外,只有将 fascial plane blocks(筋膜平面阻滞)与传统的多模式镇痛(无阻滞或安慰剂)进行比较时,fascial plane blocks(筋膜平面阻滞)才显得有效,fascial plane blocks(筋膜平面阻滞)本身不足以提供手术麻醉,似乎只有在进行小-中度手术时才有价值。尽管有大量的文献,但迄今为止,还没有任何临床情况表明 fascial plane blocks(筋膜平面阻滞)是首选的阻滞方法,它明显比其他已建立的区域阻滞方法更有效。最后,fascial plane blocks(筋膜平面阻滞)似乎几乎没有并发症,但出现的病例报告指出,在使用 fascial plane blocks(筋膜平面阻滞)时,确实存在局部麻醉全身毒性的风险。本文旨在综合 fascial plane blocks(筋膜平面阻滞)在儿科应用方面的当前知识基础。总之,目前没有令人信服的科学证据支持继续在儿童中使用 fascial plane blocks(筋膜平面阻滞),除了腹直肌鞘阻滞和可能还有经肌四头肌腰方肌阻滞。