Lukas S, Martinot P, Putman S, Lons A, Drumez E, Migaud H, Girard J
Univ. Lille, CHU Lille, ULR 4490-PMOI, F-59000, Lille, France.
Service d'Orthopédie, Hôpital Salengro, Place de Verdun, CHU Lille, F-59000, Lille, France.
Int Orthop. 2024 Jan;48(1):119-126. doi: 10.1007/s00264-023-05915-6. Epub 2023 Aug 31.
Hip arthroplasty with metal-on-metal bearings like hip resurfacing results in the release of metallic ions. In parallel, like every metallic implant, knee arthroplasty implants undergo passive corrosion. We analyzed blood levels of cobalt and chromium ions in patients who have a hip resurfacing arthroplasty and compared them to patients who have undergone knee arthroplasty at a minimum follow-up of one year. The hypothesis was that there is no difference in the ion release between hip resurfacing and knee arthroplasty.
Sixty-three patients who underwent knee arthroplasty were compared to a cohort of 132 patients who underwent hip resurfacing. The blood levels of cobalt and chromium ions were determined preoperatively and at six and 12 months postoperatively and then compared between groups. We analyzed the relationship between ion release and the change in clinical outcome scores (Harris Hip score, Oxford Hip score, Merle D'Aubigné Postel score, Oxford Knee score, International Knee Society score), the BMI, sex, physical activity, implant size and inclination of the acetabular implant (hip resurfacing patients only). Mixed linear models were used to assess the changes in ion blood levels over time.
The cobalt blood levels were higher in the first 6 months in the resurfacing group (0.87 ug/L vs 0.67 ug/L; p = 0.011), while it was higher in the knee arthroplasty group at 12 months (1.20 ug/L vs 1.41 ug/L; p = 0.0008). There were no significant differences in chromium levels during the follow-up period.
The increase in metal ion release after knee arthroplasty is as high as after hip resurfacing at the one year follow-up. The monitoring of this parameter probably should not be recommended in case of good clinicals outcomes.
金属对金属轴承的髋关节置换术(如髋关节表面置换术)会导致金属离子释放。与此同时,与所有金属植入物一样,膝关节置换术植入物会发生被动腐蚀。我们分析了接受髋关节表面置换术患者的血液中钴和铬离子水平,并将其与至少随访一年的膝关节置换术患者进行比较。假设是髋关节表面置换术和膝关节置换术之间的离子释放没有差异。
将63例接受膝关节置换术的患者与132例接受髋关节表面置换术的患者队列进行比较。术前、术后6个月和12个月测定血液中钴和铬离子水平,然后进行组间比较。我们分析了离子释放与临床结局评分变化(Harris髋关节评分、牛津髋关节评分、Merle D'Aubigné Postel评分、牛津膝关节评分、国际膝关节协会评分)、体重指数、性别、体力活动、植入物尺寸以及髋臼植入物倾斜度(仅适用于髋关节表面置换术患者)之间的关系。使用混合线性模型评估离子血液水平随时间的变化。
表面置换组前6个月钴血水平较高(0.87μg/L对0.67μg/L;p = 0.011),而膝关节置换术组在12个月时较高(1.20μg/L对1.41μg/L;p = 0.0008)。随访期间铬水平无显著差异。
在一年随访时,膝关节置换术后金属离子释放的增加与髋关节表面置换术后一样高。在临床结果良好的情况下,可能不建议监测该参数。