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远程医疗治疗伴有溃疡的婴儿复杂性血管瘤:病例报告。

Urgent Treatment of Complicated Ulcerated Infantile Hemangioma with β-Blockers via Telemedicine: A Case Report.

机构信息

Faculty of Medicine, Academy of Silesia in Katowice, Zabrze, Poland.

Bogomolets Clinic, Kyiv, Ukraine.

出版信息

Telemed J E Health. 2024 Mar;30(3):881-884. doi: 10.1089/tmj.2023.0338. Epub 2023 Aug 31.

DOI:10.1089/tmj.2023.0338
PMID:37651201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10924047/
Abstract

Infantile hemangiomas (IH) exacerbated by ulceration invariably necessitate hospitalization, although simple IHs are sometimes managed remotely. Furthermore, according to international regulations, β-blocker medication for such hemangiomas should be systemic and performed in a clinic, especially if there is infection and risk of bleeding. War in Ukraine made it impossible to hospitalize and properly examine a patient with a complex ulcerated and infected IH, forcing us to administer β-blocker timolol therapy only through telemedicine. Our case demonstrates the possibility of successful distant treatment of IH with ulcer using only a topical β-blocker carried out remotely through telemedicine, which is critical in the context of the COVID-19 pandemic, war, hostilities, or natural disasters where inpatient treatment is not available.

摘要

婴幼儿血管瘤(IH)合并溃疡者通常需要住院治疗,尽管有时也可远程管理简单的 IH。此外,根据国际规定,此类血管瘤的β受体阻滞剂药物治疗应采用全身性治疗,并在诊所进行,尤其是当存在感染和出血风险时。由于乌克兰战争,我们无法对一名患有复杂溃疡和感染性 IH 的患者进行住院治疗和适当检查,迫使我们只能通过远程医疗来给予β受体阻滞剂噻吗洛尔治疗。我们的病例证明了仅通过远程医疗使用局部β受体阻滞剂成功治疗溃疡性 IH 的可能性,这在 COVID-19 大流行、战争、敌对行动或自然灾害期间非常重要,因为在这些情况下无法提供住院治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c109/10924047/107f3b39e5ed/tmj.2023.0338_figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c109/10924047/cbab9ad1ffc6/tmj.2023.0338_figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c109/10924047/107f3b39e5ed/tmj.2023.0338_figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c109/10924047/cbab9ad1ffc6/tmj.2023.0338_figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c109/10924047/107f3b39e5ed/tmj.2023.0338_figure2.jpg

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Ukraine's most vulnerable need healthcare: Priorities during the armed conflict.乌克兰最弱势群体需要医疗保健:武装冲突期间的优先事项。
Public Health Pract (Oxf). 2022 Jul 8;4:100296. doi: 10.1016/j.puhip.2022.100296. eCollection 2022 Dec.
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Successful use of telemedicine for evaluation of infantile hemangiomas during the early COVID-19 pandemic: A cross-sectional study.远程医疗在 COVID-19 大流行早期婴幼儿血管瘤评估中的成功应用:一项横断面研究。
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婴儿血管瘤治疗进展
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Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway.普萘洛尔通过下调PI3K/Akt/eNOS/VEGF通路诱导血管瘤细胞消退。
Pediatr Blood Cancer. 2015 Aug;62(8):1414-20. doi: 10.1002/pbc.25453. Epub 2015 Mar 1.
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Biology of infantile hemangioma.婴儿血管瘤的生物学特性
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Br J Dermatol. 2015 Jan;172(1):24-32. doi: 10.1111/bjd.13388. Epub 2014 Dec 17.