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应用无创影像学方法评估 HIV 感染者的骨骼肌量和质:叙述性综述。

The use of non-invasive imaging modalities for the assessment of skeletal muscle quantity and quality in people with HIV: A narrative review.

机构信息

University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

University of Washington School of Nursing, Seattle, Washington, USA.

出版信息

HIV Med. 2023 Dec;24(12):1176-1189. doi: 10.1111/hiv.13539. Epub 2023 Aug 31.

Abstract

BACKGROUND

People with HIV (PWH) are prone to mobility impairments and physical dysfunction, with the loss of skeletal muscle quantity and quality being a major contributor to the dysfunction. Assessment of skeletal muscle is an important component of care for this patient population for early intervention and treatment. The use of non-invasive imaging techniques to evaluate skeletal muscle, such as dual X-ray absorptiometry, computer tomography and magnetic resonance imaging, has increased in popularity in recent years.

PURPOSE

This narrative review synthesizes the use of these techniques and summarizes the associations between outcomes from these imaging modalities and physical function in PWH.

摘要

背景

HIV 感染者(PWH)易出现运动功能障碍和身体机能障碍,而骨骼肌数量和质量的丧失是导致功能障碍的主要原因。评估骨骼肌是对这一患者群体进行早期干预和治疗的重要护理组成部分。近年来,使用双能 X 线吸收仪、计算机断层扫描和磁共振成像等无创影像学技术来评估骨骼肌的方法越来越普及。

目的

本叙述性综述综合了这些技术的应用,并总结了这些影像学方法的结果与 PWH 身体机能之间的关联。

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