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延迟前交叉韧带重建会增加内侧软骨损伤的发生率和严重程度。

Delaying anterior cruciate ligament reconstruction increases the rate and severity of medial chondral injuries.

机构信息

Orthopaedic Surgery and Sports Medicine Department, FIFA Medical Centre of Excellence, Croix-Rousse Hospital, Lyon University Hospital, Lyon, France.

Sydney Orthopaedic Research Institute, University of Notre Dame Australia, Hornsby and Ku-Ring Hospital, Sydney, Australia.

出版信息

Bone Joint J. 2023 Sep 1;105-B(9):953-960. doi: 10.1302/0301-620X.105B9.BJJ-2022-1437.R1.

Abstract

AIMS

The aim of this study was to evaluate the association between chondral injury and interval from anterior cruciate ligament (ACL) tear to surgical reconstruction (ACLr).

METHODS

Between January 2012 and January 2022, 1,840 consecutive ACLrs were performed and included in a single-centre retrospective cohort. Exclusion criteria were partial tears, multiligament knee injuries, prior ipsilateral knee surgery, concomitant unicompartmental knee arthroplasty or high tibial osteotomy, ACL agenesis, and unknown date of tear. A total of 1,317 patients were included in the final analysis, with a median age of 29 years (interquartile range (IQR) 23 to 38). The median preoperative Tegner Activity Score (TAS) was 6 (IQR 6 to 7). Patients were categorized into four groups according to the delay to ACLr: < three months (427; 32%), three to six months (388; 29%), > six to 12 months (248; 19%), and > 12 months (254; 19%). Chondral injury was assessed during arthroscopy using the International Cartilage Regeneration and Joint Preservation Society classification, and its association with delay to ACLr was analyzed using multivariable analysis.

RESULTS

In the medial compartment, delaying ACLr for more than 12 months was associated with an increased rate (odds ratio (OR) 1.93 (95% confidence interval (CI) 1.27 to 2.95); p = 0.002) and severity (OR 1.23 (95% CI 1.08 to 1.40); p = 0.002) of chondral injuries, compared with < three months, with no association in patients aged > 50 years old. No association was found for shorter delays, but the overall dose-effect analysis was significant for the rate (p = 0.015) and severity (p = 0.026) of medial chondral injuries. Increased TAS was associated with a significantly reduced rate (OR 0.88 (95% CI 0.78 to 0.99); p = 0.036) and severity (OR 0.96 (95% CI 0.92 to 0.99); p = 0.017) of medial chondral injuries. In the lateral compartment, no association was found between delay and chondral injuries.

CONCLUSION

Delay was associated with an increased rate and severity of medial chondral injuries in a dose-effect fashion, in particular for delays > 12 months. Younger patients seem to be at higher risk of chondral injury when delaying surgery. The timing of ACLr should be optimally reduced in this population.

摘要

目的

本研究旨在评估前交叉韧带(ACL)撕裂与手术重建(ACLr)之间的间隔时间与软骨损伤之间的关系。

方法

2012 年 1 月至 2022 年 1 月,对 1840 例连续 ACLr 进行了回顾性队列研究。排除标准为部分撕裂、多韧带膝关节损伤、同侧膝关节既往手术史、同期单髁膝关节置换术或胫骨高位截骨术、ACL 缺失以及撕裂时间未知。最终有 1317 例患者纳入最终分析,中位年龄为 29 岁(四分位间距(IQR)23 至 38)。术前 Tegner 活动评分(TAS)的中位数为 6(IQR 6 至 7)。根据 ACLr 延迟时间将患者分为四组:<3 个月(427;32%)、3 至 6 个月(388;29%)、>6 至 12 个月(248;19%)和>12 个月(254;19%)。在关节镜检查中使用国际软骨修复与关节保护协会(ICRS)分类评估软骨损伤,并使用多变量分析评估其与 ACLr 延迟之间的关系。

结果

在内侧间室中,与<3 个月相比,ACLr 延迟超过 12 个月与软骨损伤的发生率(优势比(OR)1.93(95%置信区间(CI)1.27 至 2.95);p=0.002)和严重程度(OR 1.23(95%CI 1.08 至 1.40);p=0.002)增加有关,而与年龄>50 岁的患者无关。较短的延迟时间无相关性,但总体剂量效应分析显示,内侧软骨损伤的发生率(p=0.015)和严重程度(p=0.026)有显著差异。较高的 TAS 与内侧软骨损伤的发生率(OR 0.88(95%CI 0.78 至 0.99);p=0.036)和严重程度(OR 0.96(95%CI 0.92 至 0.99);p=0.017)显著降低有关。在外侧间室中,延迟与软骨损伤之间没有相关性。

结论

延迟与内侧软骨损伤的发生率和严重程度呈剂量效应关系,特别是延迟时间>12 个月时。年轻患者在延迟手术时似乎更容易发生软骨损伤。应尽量缩短此类患者的 ACLr 时间。

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