Department of Surgery, Yokohama City University, Yokohama, Japan.
Department of Surgery, Yokohama City University, Yokohama, Japan;
In Vivo. 2023 Sep-Oct;37(5):2253-2259. doi: 10.21873/invivo.13327.
BACKGROUND/AIM: We investigated the influence of the preoperative Oral Health Assessment Tool (OHAT) score on the outcomes of patients with esophageal cancer after curative surgery.
This study included 90 patients with esophageal cancer who underwent curative surgery and who were screened with the OHAT between 2008 and 2021. The OHAT consists of eight categories with three possible scores. The risk factors for 5-year overall survival (OS) and recurrence-free survival (RFS) were identified.
Patients were divided into healthy (n=42) and unhealthy (n=48) groups. The OHAT score was identified as a significant risk factor for postoperative pneumonia (11.9% vs. 43.8%, p=0.001) and postoperative hospital stay (20.5 days vs. 50.1 days, p=0.042). The 5-year OS rate after surgery was 71.2% in the healthy group and 43.2% in the unhealthy group, which was a significant difference (p=0.015). A multivariate analysis showed that a high OHAT score was a significant independent factor for 5-year OS (p=0.034).
The OHAT score was a useful prognostic marker in patients who underwent curative surgery for esophageal cancer. To improve the oncological outcomes of patients with esophageal cancer, it is necessary to carefully plan perioperative oral/dental care using the OHAT score.
背景/目的:我们研究了术前口腔健康评估工具(OHAT)评分对接受根治性手术的食管癌患者结局的影响。
本研究纳入了 90 例 2008 年至 2021 年间接受 OHAT 筛查的接受根治性手术的食管癌患者。OHAT 由八个类别组成,每个类别有三个可能的评分。确定了 5 年总生存率(OS)和无复发生存率(RFS)的危险因素。
患者被分为健康组(n=42)和不健康组(n=48)。OHAT 评分是术后肺炎(11.9% vs. 43.8%,p=0.001)和术后住院时间(20.5 天 vs. 50.1 天,p=0.042)的显著危险因素。健康组术后 5 年 OS 率为 71.2%,不健康组为 43.2%,差异有统计学意义(p=0.015)。多因素分析显示,高 OHAT 评分是 5 年 OS 的独立显著因素(p=0.034)。
OHAT 评分是接受食管癌根治性手术患者的一种有用的预后标志物。为了提高食管癌患者的肿瘤学结局,有必要使用 OHAT 评分仔细规划围手术期口腔/牙齿护理。