奥地利高度活跃的男男性行为人群中无症状猴痘感染的证据。
No evidence of asymptomatic monkeypox infection in a highly sexually active MSM population in Austria.
机构信息
Department of Dermatology, Medical University Vienna, Vienna, Austria.
Division of Clinical Virology, Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria.
出版信息
HIV Med. 2024 Jan;25(1):150-153. doi: 10.1111/hiv.13535. Epub 2023 Aug 31.
BACKGROUND
The 2022 outbreak of monkeypox virus (MPXV) revealed new transmission routes. Incidence declined sharply in September 2022, and it remains unclear whether MPXV is circulating in asymptomatic individuals because of increased immunity.
OBJECTIVES
Our study aimed to assesss the number of asymtomatic MPXV carriers in individuals at high risk for STI.
METHODS
We analysed anal samples from asymptomatic highly sexually active men who have sex with men for the presence of MPXV.
RESULTS
We detected a high number of concomitant sexually transmitted infections but did not find a single sample with MPXV.
CONCLUSIONS
Our results indicate that the general recommendation to implement screening for MPXV is not currently justified.
背景
2022 年猴痘病毒（MPXV）的爆发揭示了新的传播途径。2022 年 9 月，发病率急剧下降，目前尚不清楚 MPXV 是否在无症状个体中传播，因为其免疫力增强。
目的
我们的研究旨在评估在性传播感染风险高的个体中无症状 MPXV 携带者的数量。
方法
我们分析了无症状、性活跃的男男性行为者的肛部分泌物样本，以检测 MPXV 的存在。
结果
我们发现了大量同时存在的性传播感染，但没有一个样本检测到 MPXV。
结论
我们的结果表明，目前不建议普遍筛查 MPXV。
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