Lina R Marlin, Sindhu R, Bharathwaj V V, Dhamodhar Dinesh, Sathiyapriya S, Prabu D, Rajmohan M
Department of Public Health Dentistry, SRM Dental College and Hospital, Ramapuram, Chennai, Tamil Nadu, India.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 1):S105-S109. doi: 10.4103/jpbs.jpbs_134_23. Epub 2023 Jul 5.
Apical periodontitis is an inflammation and destruction of the periradicular tissues due to various insults to the pulp in the form of infection, trauma, and faulty dental procedures. Conditions regarding this are treated employing root canal therapy. Recent innovations show that copper calcium hydroxide nanoparticles and their electrophoresis can be used to treat apical periodontitis effectively. To evaluate the effectiveness of copper calcium hydroxide nanoparticles in the treatment of apical periodontitis, a literature search was done using PubMed, Cochrane Central Register of controlled Trials (CENTRAL), Science Direct, and Lilacs using the MeSH (Medical Subject Heading) terms Copper calcium hydroxide, apical periodontitis, nanoparticles, and electrophoresis. Of a total of 167 articles screened, 44 were full-text articles assessed for eligibility and four articles were taken for the qualitative analysis. This review was recorded according to the PRISMA GUIDELINES. Four randomized controlled trials were included in the review process. The copper calcium hydroxide particles were compared with other root canal medicament materials. It was found that copper calcium hydroxide and its electrophoresis were used in the treatment of apical periodontitis and were found to be one of the effective methods. Copper calcium hydroxide nanoparticles were effective against the destruction of the periradicular tissues.
根尖周炎是由于感染、创伤和不当牙科操作等对牙髓的各种损害，导致根尖周组织的炎症和破坏。针对这种情况的治疗采用根管治疗。最近的创新表明，氢氧化铜钙纳米颗粒及其电泳可有效用于治疗根尖周炎。为评估氢氧化铜钙纳米颗粒治疗根尖周炎的有效性，使用医学主题词（MeSH）“氢氧化铜钙”“根尖周炎”“纳米颗粒”和“电泳”，通过PubMed、Cochrane对照试验中央注册库（CENTRAL）、Science Direct和Lilacs进行了文献检索。在总共筛选的167篇文章中，44篇为评估合格性的全文文章，4篇文章用于定性分析。本综述按照PRISMA指南记录。综述过程纳入了四项随机对照试验。将氢氧化铜钙颗粒与其他根管药物材料进行了比较。结果发现，氢氧化铜钙及其电泳用于治疗根尖周炎，是有效方法之一。氢氧化铜钙纳米颗粒对根尖周组织的破坏有效。
