可能的原发性皮肤CD8 +侵袭性亲表皮细胞毒性T细胞淋巴瘤：一例诊断难题的病例报告
Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge.
作者信息
Velarde Loya Marcela, Millan Reza Monica G, Olaya Cordova Mariana, Chavéz López Zaira D
机构信息
Internal Medicine Residency, Hospital General Presidente Lázaro Cárdenas, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Chihuahua, MEX.
Dermatology, Universidad Nacional Autónoma de México (UNAM), Chihuahua, MEX.
出版信息
Cureus. 2023 Aug 30;15(8):e44375. doi: 10.7759/cureus.44375. eCollection 2023 Aug.
Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma is a rare variety of cutaneous lymphoma. This subtype has an aggressive and quickly progressive clinical course with a survival time of 32 months from the commencement of skin lesions. This article describes a probable case of primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma in a 63-year-old female, which manifested as diffuse non-pruritic erythematous plaques and nodules. The diagnosis of this possible entity was aided by the histopathological and immunohistochemical findings, while immunohistochemistry for T-cell receptor (TCR) gamma/delta could not be done.
原发性皮肤CD8+侵袭性亲表皮细胞毒性T细胞淋巴瘤是一种罕见的皮肤淋巴瘤亚型。该亚型具有侵袭性且进展迅速的临床病程，从皮肤病变开始算起生存期为32个月。本文描述了一例63岁女性可能患有原发性皮肤CD8+侵袭性亲表皮细胞毒性T细胞淋巴瘤的病例，其表现为弥漫性非瘙痒性红斑斑块和结节。组织病理学和免疫组化结果有助于诊断这一可能的疾病实体，而T细胞受体（TCR）γ/δ的免疫组化未能进行。
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