[大鼠脑突触体膜蛋白与氧分压升高所致惊厥]
[Synaptosome membrane proteins of the rat brain in convulsions caused by increased oxygen pressure].
作者信息
Sherstnev K B, Suleĭmanov A K
出版信息
Vopr Med Khim. 1986 Jul-Aug;32(4):35-7.
PMID:3765496
Abstract
High oxygen pressure (0.7 MPa during 30-40 min) increased the quantity of high molecular proteins with simultaneous decrease in amount of low molecular proteins in rat brain synaptosomes. At the same time, the significant increase of lipoprotein fluorescence with emission at 435 nm was observed. Oxygen at high pressure inhibited incorporation of 14C-leucine into synaptosomal membrane proteins. Possible mechanisms of these alterations are discussed.
摘要
高氧压（30 - 40分钟内0.7兆帕）使大鼠脑突触体中高分子量蛋白质的数量增加，同时低分子量蛋白质的数量减少。与此同时，观察到在435纳米处发射的脂蛋白荧光显著增加。高压氧抑制了14C-亮氨酸掺入突触体膜蛋白。讨论了这些变化的可能机制。
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