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运动员与疑似儿茶酚胺能多形性室性心动过速:认识与当前知识

Athletes and suspected catecholaminergic polymorphic ventricular tachycardia: Awareness and current knowledge.

作者信息

Mascia Giuseppe, Brugada Josep, Arbelo Elena, Porto Italo

机构信息

Cardiovascular Disease Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

Arrhythmia, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Deu, Universitat de Barcelona, Barcelona, Spain.

出版信息

J Cardiovasc Electrophysiol. 2023 Oct;34(10):2095-2101. doi: 10.1111/jce.16045. Epub 2023 Sep 1.

Abstract

INTRODUCTION

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a cardiac inherited arrhythmogenic disease potentially leading to sudden cardiac death that is determined by electrical instability exacerbated by acute adrenergic tone.

METHODS AND RESULTS

Despite its life-threatening nature, CPVT remains potentially unnoticed since diagnosis may be difficult especially in apparently healthy athletes. This review summarizes current knowledge and shortcomings of CPVT, focusing on genetics, arrhythmic mechanisms, sport preparticipation screening, and current recommendations.

CONCLUSIONS

The paper captures the importance of CPVT athletes regarding the necessity of risk stratification, as well as the importance of maintaining a healthy lifestyle.

摘要

引言

儿茶酚胺能性多形性室性心动过速(CPVT)是一种遗传性心脏致心律失常疾病,可能导致心源性猝死,其由急性肾上腺素能张力加剧的电不稳定所决定。

方法与结果

尽管CPVT具有危及生命的性质,但由于诊断可能困难,尤其是在看似健康的运动员中,它仍可能未被注意到。本综述总结了CPVT的当前知识和不足,重点关注遗传学、心律失常机制、运动前筛查及当前建议。

结论

本文阐述了CPVT运动员进行风险分层的必要性以及保持健康生活方式的重要性。

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