Singer R E, Dutton W G
J Dent Res. 1979 Jun;58(6):1634-9. doi: 10.1177/00220345790580061301.
The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In contrast, endotoxin was shown to inhibit incorporation of proline into cell protein to a significantly greater extent.
测定了大肠杆菌内毒素对小鼠L929细胞增殖、DNA合成、蛋白质合成和脯氨酸掺入的影响。结果发现，抑制细胞增殖的内毒素水平会引发对DNA合成和整体细胞蛋白质合成的类似抑制。相比之下，内毒素对脯氨酸掺入细胞蛋白质的抑制作用要显著得多。
