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一项比较三种不同方法估算新生儿鼻胃管插入长度的随机临床试验:中国单中心经验

A Randomized Clinical Trial to Compare Three Different Methods for Estimating Orogastric Tube Insertion Length in Newborns: A Single-Center Experience in China.

作者信息

Chen Jun, Huang Chaomei, Fang Xiaoling, Liu Lijun, Dai Yiheng

出版信息

Neonatal Netw. 2023 Aug 1;42(5):276-283. doi: 10.1891/NN-2023-0016.

DOI:10.1891/NN-2023-0016
PMID:37657808
Abstract

Orogastric (OG) and nasogastric (NG) tubes are frequently used in the NICU. Obtaining a relatively accurate estimated length before insertion could significantly reduce complications. While previous studies have mainly focused on the NG tube, OG tubes are more commonly used in China. The objective was to determine whether there were differences in the rate of accurate placement among the adapted nose-ear-xiphoid (NEX) method, nose-ear-midway to the umbilicus (NEMU) method, and weight-based (WB) equation in estimating the OG tube insertion distance. A randomized, controlled, open-label clinical trial to compare the three methods was conducted in a single center. After enrollment, newborns were randomly assigned into three groups. By radiological assessment, the anatomical region for OG tube placement was analyzed. The primary metric was the tip within the gastric body, and the second metric was strictly accurate placement defined as the tube was not looped back within the stomach and the end was located more than 2 cm but less than 5 cm into the stomach, referred to as T10. This study recruited 156 newborns with the majority being preterm infants ( = 96; 61.5 percent), with an average birth weight of 2,200.8 ± 757.8 g. For the WB equation, 96.2 percent (50 cases) of the OG tubes were placed within the stomach, and the rates were 78.8 percent (41 cases) in the adapted NEX and NEMU methods. The strictly accurate placement rates were highest for the WB equation at 80.8 percent (42/52), followed by the adapted NEX method at 65.4 percent (34/52), and the NEMU method at 57.7 percent (30/52). The WB equation for estimating the insertion depth of the OG tube in newborn infants resulted in more precise placement compared to the adapted NEX and NEMU methods.

摘要

胃管(OG)和鼻胃管(NG)在新生儿重症监护病房(NICU)中经常使用。在插入前获得相对准确的估计长度可显著减少并发症。虽然先前的研究主要集中在鼻胃管,但胃管在中国更常用。目的是确定在估计胃管插入距离时,改良的鼻-耳-剑突(NEX)法、鼻-耳-脐中点(NEMU)法和基于体重(WB)的公式在准确放置率上是否存在差异。在单一中心进行了一项随机、对照、开放标签的临床试验,以比较这三种方法。入组后,将新生儿随机分为三组。通过放射学评估,分析胃管放置的解剖区域。主要指标是胃管尖端位于胃体部,次要指标是严格准确放置,定义为胃管在胃内无折返且末端位于胃内超过2 cm但小于5 cm处,称为T10。本研究招募了156名新生儿,其中大多数为早产儿(n = 96;61.5%),平均出生体重为2200.8±757.8 g。对于基于体重的公式,96.2%(50例)的胃管放置在胃内,改良的NEX法和NEMU法的放置率分别为78.8%(41例)。严格准确放置率最高的是基于体重的公式,为80.8%(42/52),其次是改良的NEX法,为65.4%(34/52),NEMU法为57.7%(30/52)。与改良的NEX法和NEMU法相比,基于体重的公式用于估计新生儿胃管插入深度时放置更精确。

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