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视频辅助治疗复杂性肛瘘的长期效果:又一个破灭的梦想?

Long term results of video-assisted anal fistula treatment for complex anal fistula: another shattered dream?

作者信息

La Torre Marco, Goglia Marta, Micarelli Alessandro, Fiori Enrico, D'Andrea Vito, Grossi Ugo, Tierno Simone Maria, Tomassini Federico, Gallo Gaetano

机构信息

Department of Surgery, Sapienza University of Rome, Rome, Italy.

Department of General Surgery, Sant'Andrea University Hospital, Sapienza University of Rome, Rome, Italy.

出版信息

Colorectal Dis. 2023 Oct;25(10):2017-2023. doi: 10.1111/codi.16732. Epub 2023 Sep 1.

Abstract

AIM

Complex anal fistula represents a burden for patients, and its management is a challenge for surgeons. Video-assisted anal fistula treatment (VAAFT) is one sphincter-sparing technique. However, data on its long-term effectiveness are scant. We aimed to explore the outcomes of VAAFT in a retrospective cohort of patients referred to a tertiary centre.

METHOD

Consecutive adult patients with a minimum of 2 years' follow-up after VAAFT were reviewed. Patients were followed up to 5 years postoperatively. Failure was defined as incomplete healing of the external orifice(s) during the first 6 months. Recurrence was defined as new radiologically and/or clinically confirmed onset of the fistula after primary healing. A generalized linear model was fitted to evaluate the association between failure and sociodemographic characteristics. Predictors of recurrence were determined in a subgroup analysis of patients found to be free from disease at 6 months postoperatively.

RESULTS

Overall, 106 patients (70% male; mean age 41 years) were reviewed. Of these 86% had a previous seton placement. Fistulas were either high trans-sphincteric (74%), suprasphincteric (12%) or extrasphincteric (13%). Eight (7%) patients experienced postoperative complications, none of which required reintervention. Mean follow-up was 53 ± 13.2 months. VAAFT failed in 14 (13%) patients. The overall recurrence rate ranged from 29% at 1 year to 63% at 5 years. Multiple external orifices, suprasphincteric fistula, younger age, previous surgery and higher complexity of the fistulous tract were independent risk factors for recurrence.

CONCLUSION

VAAFT is a safe sphincter-sparing technique. The initially high success rate decreases over time and relates to a higher degree of complexity.

摘要

目的

复杂性肛瘘给患者带来负担,其治疗对外科医生而言是一项挑战。视频辅助肛瘘治疗(VAAFT)是一种保留括约肌的技术。然而,关于其长期疗效的数据却很少。我们旨在探讨在一个转诊至三级中心的回顾性队列患者中VAAFT的治疗结果。

方法

对接受VAAFT治疗后至少随访2年的成年患者进行回顾性研究。患者术后随访5年。失败定义为术后前6个月外口未完全愈合。复发定义为初次愈合后经放射学和/或临床确诊的肛瘘新发病例。采用广义线性模型评估失败与社会人口学特征之间的关联。在术后6个月无疾病的患者亚组分析中确定复发的预测因素。

结果

总体而言,共回顾了106例患者(70%为男性;平均年龄41岁)。其中86%的患者先前已放置挂线。肛瘘类型为高位经括约肌型(74%)、括约肌上型(12%)或括约肌外型(13%)。8例(7%)患者出现术后并发症,均无需再次干预。平均随访时间为53±13.2个月。14例(13%)患者VAAFT治疗失败。总体复发率从1年时的29%到5年时的63%不等。多个外口、括约肌上型肛瘘、年轻、既往手术史以及瘘管复杂性较高是复发的独立危险因素。

结论

VAAFT是一种安全的保留括约肌技术。最初较高的成功率会随着时间下降,且与更高的复杂性相关。

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