不明原发灶癌最终诊断为低分化前列腺癌：病例报告。
Cancer of unknown primary eventually diagnosed as poorly differentiated prostate cancer: a case report.
机构信息
Department of Medical Oncology, Tonan Hospital, Sapporo, Hokkaido, Japan.
Rumoi City Hospital Department of Gastroenterology, Rumoi, Hokkaido, Japan.
出版信息
J Med Case Rep. 2023 Sep 3;17(1):376. doi: 10.1186/s13256-023-04118-2.
BACKGROUND
Prostate cancer has been well known to have a high prevalence among middle-aged and older men, with high incidence of metastases to the bone-the main metastatic site. However, prostate cancer among those less than 50 years of age is extremely rare, and neck swelling is seldom the initial symptom.
CASE PRESENTATION
We herein report case of a 47-year-old Japanese male with poorly differentiated prostate cancer that had been initially diagnosed as a cancer of unknown primary with multiple lymph node and bone metastases before reaching a definitive diagnosis. The patient has been started on endocrine therapy and is currently alive without progression.
DISCUSSION AND CONCLUSION
When locating the primary lesion in men with cancer of unknown primary, it is important to consider the possibility of prostate cancer, confirm serum prostate-specific antigen levels, and perform local prostate evaluation.
背景
前列腺癌在中年和老年男性中患病率较高，且易发生骨转移——主要的转移部位。然而，50 岁以下的前列腺癌极为罕见，且颈部肿胀很少是首发症状。
病例介绍
我们在此报告一例 47 岁的日本男性，患有低分化前列腺癌，最初被诊断为不明原发灶癌，伴有多处淋巴结和骨转移，之后才明确诊断。该患者已开始接受内分泌治疗，目前病情无进展，仍存活。
讨论与结论
在诊断不明原发灶癌的男性中定位原发病灶时，需要考虑前列腺癌的可能性，确认血清前列腺特异性抗原水平，并进行局部前列腺评估。
Zotero 插件