强效诱变剂3,5,8-三甲基-3H-咪唑并[4,5-f]喹喔啉-2-胺的合成。
Synthesis of the potent mutagen 3,5,8-trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine.
作者信息
Nyhammar T, Grivas S
出版信息
Acta Chem Scand B. 1986 Aug;40(7):583-7. doi: 10.3891/acta.chem.scand.40b-0583.
Abstract
The mutagenic title compound (5,8-DiMeIQx) was synthesized by two different routes: from 2-methyl-4,6-dinitroaniline; and from 4-chloro-2-methyl-6-nitroaniline. The latter and more convenient route involved 2,1,3-benzoselenadiazole intermediates.
摘要
致突变性标题化合物（5,8-二甲基异喹啉）通过两种不同途径合成：由2-甲基-4,6-二硝基苯胺合成；以及由4-氯-2-甲基-6-硝基苯胺合成。后一种且更简便的途径涉及2,1,3-苯并硒二唑中间体。
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