Department of Medicine, Nazarbayev University School of Medicine, Kerei-Zhanibek Str. 5/1, Astana, 010000, Kazakhstan.
Clinical Academic Department of Pediatrics, National Research Center of Mother and Child Health, University Medical Center, Astana, 010000, Kazakhstan.
Eur J Pediatr. 2023 Nov;182(11):4807-4832. doi: 10.1007/s00431-023-05155-1. Epub 2023 Sep 4.
Erythema ab igne is a dermatological condition resulting from repeated low-grade heat exposure (below the burning point), which can variably manifest with reticulated erythema and skin hyperpigmentation. Not infrequently, the cause of such a skin disorder is not immediately evident or reported by patients, especially if these are children. Compared to adults, erythema ab igne is rare in children and, if the general practitioners and pediatricians are not aware of this disorder, pediatric patients are often addressed to rheumatologists and/or undergo useless immunological investigations. Here, we performed a systematic case-based review, which finally included 32 cases of pediatric erythema ab igne (in addition to our new clinical report), and discussed the main clinical aspects and issues of this clinical entity in children. In detail, similarities of erythema ab igne with livedo reticularis and/or vasculitis-related rashes sometimes can lead to perform a panel of immunological investigations, which could be avoided. Indeed, our analysis emphasizes the importance of a careful and complete patient's anamnesis, including active questioning about the potential exposure to any physical agents (including heat sources) that may cause dermatological lesions. We also highlight some peculiarities in terms of location and heat injury in children developing erythema ab igne, based on the presence or absence of comorbidities.
The occurrence of erythema ab igne in children (and especially in adolescents) is likely to increase in the next years because of the greater and sometimes inappropriate use of technological devices. Physicians should be aware of this condition in order to prevent patients from useless investigations, especially in the differential diagnosis of rheumatic disorders. A careful and complete patient's history with active questioning about the potential exposure to heating source is often decisive to diagnose erythema ab igne.
• Erythema ab igne is a dermatological condition which is mainly described in adults exposed to heating source at the workplace.
• The occurrence of erythema ab igne in children is likely to increase in the next years because of the greater and sometimes inappropriate use of technological devices. • Erythema ab igne in children can be classified in two main categories, based on the presence or absence of comorbidity. • A careful and complete anamnesis (including the active questioning about potential exposure to any heating source) is the mainstay for diagnosing erythema ab igne in children.
红斑性火激病是一种由反复接触低强度热(低于燃点)引起的皮肤病,其表现形式多种多样,包括网状红斑和皮肤色素沉着过度。这种皮肤病的病因并不总是显而易见的,也不会被患者报告,尤其是儿童。与成年人相比,红斑性火激病在儿童中较为罕见,如果普通医生和儿科医生没有意识到这种疾病,儿科患者通常会被转介给风湿病医生,或者接受不必要的免疫检查。在这里,我们进行了一项系统的基于病例的综述,最终纳入了 32 例儿科红斑性火激病病例(除了我们的新临床报告),并讨论了该疾病在儿童中的主要临床方面和问题。详细地说,红斑性火激病与网状青斑和/或血管炎相关皮疹的相似之处有时会导致进行一系列免疫检查,而这些检查是可以避免的。事实上,我们的分析强调了仔细和完整的患者病史的重要性,包括主动询问任何可能导致皮肤损伤的物理因素(包括热源)的潜在暴露情况。我们还根据是否存在合并症,强调了儿童红斑性火激病在发病部位和热损伤方面的一些特点。
由于科技设备的广泛应用和有时使用不当,未来几年儿童(尤其是青少年)中红斑性火激病的发病率可能会增加。医生应该意识到这种疾病,以避免患者进行不必要的检查,特别是在风湿性疾病的鉴别诊断中。仔细和完整的患者病史,主动询问潜在热源暴露情况,通常是诊断红斑性火激病的关键。
•红斑性火激病是一种主要发生在暴露于工作场所热源的成年人中的皮肤病。
•由于科技设备的广泛应用和有时使用不当,未来几年儿童中红斑性火激病的发病率可能会增加。•儿童红斑性火激病可分为两类,主要依据是否存在合并症。•仔细和完整的病史(包括主动询问潜在热源暴露情况)是诊断儿童红斑性火激病的主要依据。