Sun Y M, Li G Y, Lu H Y
Institute for HIV/AIDS and STD Prevention and Control,Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2023 Aug 10;44(8):1264-1269. doi: 10.3760/cma.j.cn112338-20230109-00020.
To examine the willingness of HIV non-occupational post-exposure prophylaxis (nPEP) among MSM and factors related were also assessed. The respondent-driven sampling method was used to recruit MSM for a face-to-face interview with a structured questionnaire,the sample size was estimated at 600 subjects. Demographic data, sexual behavior, awareness, and willingness regarding nPEP were collected. The factors related to willingness to nPEP were assessed using complex logistic regression. A total of 14 rounds were recruited and 608 MSM subjects were included in the study. The average age was (41.6±11.0) years. 55.4% (95%: 49.4%-59.4%) were aware of nPEP, and 4.5% (95%: 2.9%-6.2%) have used its. 35.9% (95%: 31.1%-40.7%) expressed interest in taking nPEP if needed. Among the reasons for not being willing to take nPEP, 68.9% (244/354) were never heard of nPEP, and 24.6% (87/354) were a fluke mentality. The multivariate logistic analysis results showed that the willingness of nPEP awareness of MSM was related to the group aged 25-39 years old (a=1.80, 95%: 1.01-3.20), knowing a group of HIV prevention knowledge (a=2.43, 95%: 1.52-3.90), group of consistent condom use in anal sex in the past half of year (a=1.76, 95%: 1.11-2.79). The use rate of nPEP among MSM in Beijing was low, and the willingness to use in the future also needs to be improved. The training of social organizations should be strengthened to improve the role of peer education in promoting nPEP.
为调查男男性行为者(MSM)进行HIV非职业性暴露后预防(nPEP)的意愿,并评估相关影响因素。采用应答者驱动抽样方法招募MSM进行面对面的结构化问卷调查,样本量估计为600名对象。收集了人口学数据、性行为、对nPEP的知晓情况及意愿等信息。采用复杂逻辑回归分析nPEP意愿的相关影响因素。共招募了14轮,608名MSM纳入研究。平均年龄为(41.6±11.0)岁。55.4%(95%置信区间:49.4%-59.4%)知晓nPEP,4.5%(95%置信区间:2.9%-6.2%)曾使用过nPEP。35.9%(95%置信区间:31.1%-40.7%)表示在需要时愿意服用nPEP。在不愿意服用nPEP的原因中,68.9%(244/354)从未听说过nPEP,24.6%(87/354)存在侥幸心理。多因素逻辑分析结果显示,MSM对nPEP的知晓意愿与25-39岁年龄组有关(α=1.80,95%置信区间:1.01-3.20),知晓一组HIV预防知识(α=2.43,95%置信区间:1.52-3.90),过去半年在肛交中坚持使用避孕套(α=1.76,95%置信区间:1.11-2.79)。北京MSM中nPEP的使用率较低,未来的使用意愿也有待提高。应加强社会组织培训,以提升同伴教育在促进nPEP方面的作用。