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中国男同性恋、双性恋和其他与男性发生性行为者中非职业性接触后预防(nPEP)的知晓率和接受率:一项横断面研究。

Awareness and uptake of non-occupational post-exposure prophylaxis (nPEP) among gay, bisexual and other men who have sex with men in China: a cross-sectional study.

机构信息

School of Public Health, Sun Yat-sen University, Guangzhou, China.

School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.

出版信息

Psychol Health Med. 2024 Jan-Jun;29(2):223-235. doi: 10.1080/13548506.2022.2125993. Epub 2022 Sep 19.

Abstract

Non-occupational post-exposure prophylaxis (nPEP) is recommended to reduce the likelihood of HIV infection after potential exposure. However, little is known about this practice among Chinese gay, bisexual and other men who have sex with men (GBM). GBM were enrolled from both centers for disease prevention and control (CDCs) and community health centers in six cities in China. Multivariable logistics regression was used to assess factors associated with awareness of and willingness to use nPEP. A total of 516 eligible GBM were included, 67.2% of whom were aware of nPEP, 76.0% were willing to use nPEP, and 2.3% had ever used nPEP. GBM who had college or higher education, had disclosed sexual orientation, had increased number of male sex partners in the last 6 months, and had ever tested for HIV were more likely to be aware of nPEP. Willingness to use nPEP was significantly associated with college or higher education, STI history, gay app use, and awareness of nPEP prior to study. Uptake of nPEP is still low among MSM in China. Efforts are needed to improve awareness of and access to nPEP among GBM, especially those at higher risk of HIV infection.

摘要

非职业性暴露后预防(nPEP)被推荐用于降低潜在暴露后 HIV 感染的可能性。然而,中国人同性恋、双性恋和其他男男性行为者(MSM)中对此做法的了解甚少。在六个中国城市的疾病预防控制中心(CDC)和社区卫生中心招募了 MSM。采用多变量逻辑回归评估与知晓和愿意使用 nPEP 相关的因素。共纳入 516 名符合条件的 MSM,其中 67.2%知晓 nPEP,76.0%愿意使用 nPEP,2.3%曾使用过 nPEP。具有大学或以上学历、已公开性取向、过去 6 个月中有更多男性性伴侣、曾进行过 HIV 检测的 MSM 更有可能知晓 nPEP。愿意使用 nPEP 与大学或以上学历、性传播感染史、同性恋应用程序的使用以及在研究前知晓 nPEP 显著相关。中国 MSM 中 nPEP 的使用率仍然较低。需要努力提高 GBM,特别是那些感染 HIV 风险较高的人群对 nPEP 的认识和获得途径。

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