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处方兴奋剂药物:过去十年、新冠疫情应对前后的趋势。

Prescribed stimulant medications: Trends in the last decade, pre and post COVID-19 response.

作者信息

Kim Meelee L, Dalvi Netrali, Valerio Danielle DeNufrio, Strickler Gail K, Young Leonard D

机构信息

Institute for Behavioral Health, Heller School for Social Policy and Management, Brandeis University, Waltham, MA, USA.

Office of Prescription Monitoring and Drug Control, Bureau of Health Professional Licensure, Massachusetts Department of Public Health, Boston, MA, USA.

出版信息

Explor Res Clin Soc Pharm. 2023 Aug 9;11:100314. doi: 10.1016/j.rcsop.2023.100314. eCollection 2023 Sep.

Abstract

BACKGROUND

Recent studies indicate that COVID-19 has had a significant impact on access and continuity to opioid and benzodiazepine medications; little is known about its effect on access to and utilization of stimulant medications.

OBJECTIVE

To investigate trends of dispensed stimulant medications in relation to the COVID-19 pandemic response.

METHODS

Stimulant prescriptions dispensed during 2011-2021 were analyzed using the Massachusetts Prescription Drug Monitoring Program (PDMP), the state's data repository for all controlled substance medications dispensed to residents from retail pharmacies and out of state mail-order pharmacies. Statewide trends were estimated by age group, sex, and stimulant-naïve patients (individuals with no stimulant prescription in the prior one-year period).

RESULTS

Overall, stimulant prescriptions increased 70% from 2011 to 2021. Wide differences by sex and age groups were found pre and post COVID response periods. Between 2019 and 2021, stimulant prescriptions for males 12-18 years old decreased 14.6% compared to 0.9% for females. Female stimulant-naïve patients ages 25-34 increased more than males between 2019 and 2021 (11.6% compared to <1%, respectively) and females ages 35-44 increased 4.1% while males decreased by 2.7%.

CONCLUSIONS

Administrators, clinicians, and policy makers should closely monitor stimulant prescribing trends, a critical step in improving access to and quality of care.

摘要

背景

近期研究表明,新冠疫情对阿片类药物和苯二氮䓬类药物的获取与连续性产生了重大影响;而对于其对兴奋剂类药物获取和使用的影响,人们了解甚少。

目的

调查与新冠疫情应对相关的兴奋剂类药物配药趋势。

方法

利用马萨诸塞州处方药监测项目(PDMP)分析了2011年至2021年期间发放的兴奋剂类处方,该项目是该州所有从零售药店和州外邮购药店发放给居民的管制类药物的数据储存库。按年龄组、性别和未使用过兴奋剂的患者(前一年无兴奋剂处方的个体)估算全州范围的趋势。

结果

总体而言,2011年至2021年期间兴奋剂类处方增加了70%。在新冠疫情应对前后,性别和年龄组之间存在很大差异。2019年至2021年期间,12至18岁男性的兴奋剂类处方减少了14.6%,而女性为0.9%。2019年至2021年期间,25至34岁未使用过兴奋剂的女性患者增加幅度超过男性(分别为11.6%和不到1%),35至44岁女性增加了4.1%,而男性减少了2.7%。

结论

管理人员、临床医生和政策制定者应密切监测兴奋剂类处方趋势,这是改善医疗服务可及性和质量的关键一步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c665/10470379/b54e3cf2d70a/gr1.jpg

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