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即刻修复的阴茎骨折:年龄是术后长期功能结局的唯一预测因素。

Immediately repaired penile fractures: age is the only predictor of postoperative long-term functional outcomes.

作者信息

Avci Ibrahim Erkut, Yilmaz Hasan, Cinar Naci Burak, Akdas Enes Malik, Teke Kerem, Culha Mustafa Melih

机构信息

Department of Urology, School of Medicine, Kocaeli University, 41380, Kocaeli, Turkey.

出版信息

Sex Med. 2023 Aug 29;11(4):qfad048. doi: 10.1093/sexmed/qfad048. eCollection 2023 Aug.

Abstract

BACKGROUND

Penile fractures can lead to many functional complications, especially erectile dysfunction (ED). Few studies have evaluated the factors that predict late complications of an immediately repaired penile fracture.

AIM

To identify the potential predictors of long-term poor functional outcomes following immediate surgical intervention for penile fractures.

METHODS

Sixty-eight consecutive patients with suspected penile fracture between 2003 and 2022 were retrospectively reviewed. Functional outcomes, postoperative complications, and follow-up duration were obtained from the records of follow-up visits. Age at presentation, location and length of the tunical tear, the presence of urethral rupture, and time to surgery were all analyzed as potential risk factors for postoperative functional outcomes.

OUTCOMES

Postoperative erectile function and intercourse satisfaction were measured by the IIEF-5 (the 5-item version of the International Index of Erectile Function). Penile curvature, a palpable nodule, and paresthesia/numbness were detected by physical examination. Uroflowmetry was used to assess urinary flow in patients who underwent urethral repair.

RESULTS

Fifty-eight patients were analyzed. The mean ± SD age was 38.1 ± 10.4 years; the median follow-up was 79.0 months (range, 13-180); the median time to surgery was 9.8 hours (4-30); and the median tunical tear length was 15.5 mm (4-40). Urethral rupture was observed in 8 patients (13.8%). In univariable analyses, urethral rupture was associated with postoperative complications ( = .034). In addition, age at presentation and tunical tear size were significantly associated with postoperative complications and ED ( < .05). However, in multivariable analyses, only age at presentation significantly predicted postoperative complications and ED ( = .004 and  = .037).

CLINICAL IMPLICATIONS

Age at presentation is the most important factor determining the prognosis of immediate surgical repair of the penile fracture, which aids in predicting potential complications and discussing them with patients prior to surgical intervention and during the follow-up period.

STRENGTHS AND LIMITATIONS

The study's retrospective design is an important limitation. Furthermore, there were no data on an IIEF-5 outcome measuring preoperative erectile function.

CONCLUSION

These results revealed an association between (1) urethral rupture, longer tunical tears, and older age and (2) the development of late complications. The remarkable finding of this study was that age at presentation was the only significant predictor of functional complications based on multivariable analyses. This relationship also remained robust in tests evaluating the covariance of the effects of aging on ED.

摘要

背景

阴茎骨折可导致多种功能并发症,尤其是勃起功能障碍(ED)。很少有研究评估预测阴茎骨折即时修复后晚期并发症的因素。

目的

确定阴茎骨折即时手术干预后长期功能预后不良的潜在预测因素。

方法

回顾性分析2003年至2022年间连续68例疑似阴茎骨折的患者。从随访记录中获取功能预后、术后并发症及随访时间。将就诊时年龄、白膜撕裂的位置和长度、尿道破裂的存在情况以及手术时间均作为术后功能预后的潜在危险因素进行分析。

结果

对58例患者进行了分析。平均年龄±标准差为38.1±10.4岁;中位随访时间为79.0个月(范围13 - 180个月);中位手术时间为9.8小时(4 - 30小时);中位白膜撕裂长度为15.5毫米(4 - 40毫米)。8例患者(13.8%)出现尿道破裂。在单变量分析中,尿道破裂与术后并发症相关(P = 0.034)。此外,就诊时年龄和白膜撕裂大小与术后并发症及勃起功能障碍显著相关(P < 0.05)。然而,在多变量分析中,仅就诊时年龄显著预测术后并发症及勃起功能障碍(P = 0.004和P = 0.037)。

临床意义

就诊时年龄是决定阴茎骨折即时手术修复预后的最重要因素,有助于在手术干预前及随访期间预测潜在并发症并与患者进行讨论。

优点和局限性

本研究的回顾性设计是一个重要局限。此外,没有关于术前勃起功能的国际勃起功能指数5项版(IIEF - 5)结果测量的数据。

结论

这些结果揭示了(1)尿道破裂、较长的白膜撕裂和较高年龄与(2)晚期并发症发生之间的关联。本研究的显著发现是,基于多变量分析,就诊时年龄是功能并发症的唯一显著预测因素。在评估衰老对勃起功能障碍影响的协方差测试中,这种关系也依然稳固。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ca/10468742/30feb7169775/qfad048f1.jpg

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