伴有不寻常珊瑚样多形性病变的非人乳头瘤病毒阴茎鳞状细胞癌。
Non-human papillomavirus penile squamous cell carcinoma with unusual coral-like polymorphic lesion.
作者信息
Sherryn Sherryn, Sanjaya I Putu Gde, Rahayu Luh Dewi
机构信息
Department of Clinical Medicine, Universitas Cenderawasih, Jayapura, Papua, Indonesia.
Department of Urology, Mangusada General Hospital (RSD Mangusada), Badung, Bali, Indonesia.
出版信息
Urol Ann. 2023 Jul-Sep;15(3):337-339. doi: 10.4103/ua.ua_146_22. Epub 2023 Jul 17.
Penile cancer is a rare malignancy of the male genital system. Approximately 98% of penile cancer corresponds to squamous cell carcinoma (SCC), with further morphological and molecular classification into human papillomavirus (HPV) dependent and non-HPV SCC. Compared to HPV-induced SCC, non-HPV SCC appeared to have a worse prognosis. Here, we present a case of an uncircumcised male with an unusual coral-like polymorphic lesion, and confirmed histopathology of well-differentiated non-HPV penile SCC with rapid growth progression.
阴茎癌是男性生殖系统的一种罕见恶性肿瘤。大约98%的阴茎癌为鳞状细胞癌（SCC），根据形态学和分子特征可进一步分为人乳头瘤病毒（HPV）相关性和非HPV相关性SCC。与HPV诱导的SCC相比，非HPV相关性SCC的预后似乎更差。在此，我们报告一例未行包皮环切术的男性患者，其阴茎出现了一种不寻常的珊瑚状多形性病变，经组织病理学确诊为高分化非HPV相关性阴茎SCC，且生长进展迅速。
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