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二尖瓣狭窄与单纯三尖瓣反流:同期进行二尖瓣和三尖瓣置换术的尸检患者与同期进行二尖瓣置换术和三尖瓣瓣环成形术的尸检患者的比较。

Mitral valve stenosis and pure tricuspid valve regurgitation: comparison of necropsy patients having simultaneous mitral and tricuspid valve replacements with necropsy patients having simultaneous mitral valve replacement and tricuspid valve anuloplasty.

作者信息

Sullivan M F, Roberts W C

出版信息

Am J Cardiol. 1986 Oct 1;58(9):768-80. doi: 10.1016/0002-9149(86)90353-x.

DOI:10.1016/0002-9149(86)90353-x
PMID:3766418
Abstract

Clinical and morphologic observations are described in 30 patients (23 [77%] of whom were in functional class III or IV) who underwent replacement of the mitral valve for mitral stenosis and either simultaneous replacement (13 patients, group I) or anuloplasty (17 patients, group II) of the tricuspid valve for pure tricuspid valve regurgitation. Comparison of the 13 patients in group I with the 17 patients in group II disclosed similar mean ages (55 vs 58 years), similar average preoperative right ventricular systolic pressures (64 vs 61 mm Hg), similar average right atrial mean pressures (10 vs 9 mm Hg), similar average left ventricular systolic pressures (126 vs 120 mm Hg), similar average pulmonary artery wedge-left ventricular mean diastolic pressures (16 vs 18 mm Hg), similar cardiac indexes (2.1 vs 2.0 liters/min/m2), similar mean heart weights (507 vs 535 g), and similar percents with grossly visible foci of left ventricular necrosis (15% vs 12%) and fibrosis (23% vs 12%). Of the 13 patients in group I, 10 (77%) died early (less than or equal to 60 days of tricuspid valve replacement) and 3 (23%) died late (29, 37 and 120 months); of the 17 patients in group II, 14 (82%) died early and 3 (18%) died late (4, 9 and 98 months). The causes of early death in the 2 groups were different: of the 10 patients in group I who died early, the cause was excessive bleeding in 5, low cardiac output of undetermined etiology in 3, dysfunction of both prostheses in 1 and cerebral insult in 1; of the 14 patients in group II who died early, none died from excessive bleeding, 4 from decreased cardiac output of uncertain cause, 5 from left ventricular inflow obstruction (produced by a Starr-Edwards ball-valve prosthesis in 4 and from a Starr-Edwards disc prosthesis in 1), 1 from left ventricular outflow obstruction (by a porcine bioprosthesis), 2 from technical mishaps (incision into left ventricular free wall with rupture in 1 and ligation of the left circumflex coronary artery with resulting acute myocardial infarction in 1) and 2 died suddenly for reasons not determined. Of the 6 patients dying greater than 60 days after operation, 4 died from chronic congestive cardiac failure, 1 from a cerebral embolus and 1 from prosthetic valve endocarditis.

摘要

对30例患者(其中23例[77%]为心功能Ⅲ或Ⅳ级)进行了临床和形态学观察,这些患者因二尖瓣狭窄接受二尖瓣置换术,并因单纯三尖瓣反流同时接受三尖瓣置换术(13例,Ⅰ组)或三尖瓣成形术(17例,Ⅱ组)。将Ⅰ组的13例患者与Ⅱ组的17例患者进行比较,发现两组患者的平均年龄相似(55岁对58岁),术前右心室收缩压平均值相似(64 mmHg对61 mmHg),右心房平均压平均值相似(10 mmHg对9 mmHg),左心室收缩压平均值相似(126 mmHg对120 mmHg),肺动脉楔压-左心室平均舒张压平均值相似(16 mmHg对18 mmHg),心脏指数相似(2.1 L/min/m²对2.0 L/min/m²),平均心脏重量相似(507 g对535 g),左心室坏死肉眼可见病灶的百分比相似(15%对12%),纤维化百分比相似(23%对12%)。Ⅰ组的13例患者中,10例(7

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