Cao Jianghui, Gong Anna, An Peng, Chen Ran, Chen Hong, Wang Yong, Gao Ping
Department of Radiology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Department of Radiology, Hubei Provincial Clinical Research Center for Parkinson's Disease, Xiangyang Key Laboratory of Movement Disorders, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Exp Ther Med. 2023 Aug 11;26(4):464. doi: 10.3892/etm.2023.12163. eCollection 2023 Oct.
IgG4 masses in the bilateral distal ureters are rare and frequently misdiagnosed. The present study reported the case of a 55-year-old male patient with IgG4-related disease (IgG4-RD) who had symmetrical soft tissue masses of the bilateral distal ureters found on magnetic resonance imaging (MRI) with a significant increase in the serum levels of IL-6, IgG4 and IgE. Regarding treatment, this patient received prednisone acetate tablets (40 mg/day) and mycophenolate mofetil dispersible tablets (1 g/day). During the follow-up, significant reductions in the levels of IgG4 and IgE were found after 30 days. MRI after 6 months indicated complete disappearance of the masses. The prognosis has been good so far. In clinical practice, it is necessary to consider the possibility of IgG4-RD in cases with soft tissue masses surrounding both ureters and elevated levels of serum IgG4.
双侧远端输尿管的IgG4肿块较为罕见,且常被误诊。本研究报告了一例55岁男性IgG4相关疾病(IgG4-RD)患者,其在磁共振成像(MRI)上发现双侧远端输尿管有对称性软组织肿块,血清白细胞介素-6、IgG4和IgE水平显著升高。在治疗方面,该患者接受了醋酸泼尼松片(40毫克/天)和吗替麦考酚酯分散片(1克/天)治疗。随访期间,30天后发现IgG4和IgE水平显著降低。6个月后的MRI显示肿块完全消失。迄今为止,预后良好。在临床实践中,对于双侧输尿管周围有软组织肿块且血清IgG4水平升高的病例,有必要考虑IgG4-RD的可能性。