Greene G M, Lain D, Sherwin R M, Wilson J E, McManus B M
Am J Med. 1986 Oct;81(4):727-33. doi: 10.1016/0002-9343(86)90568-1.
Giant cell arteritis rarely presents as clinically advanced extra-ocular ischemia or gangrene. Clinically isolated leg involvement with amputation is even more unusual. A 69-year-old woman is described who had giant cell arteritis necessitating bilateral leg amputations. No other clinical sequelae have ensued during a four-year follow-up period. Temporal artery biopsy subsequent to the amputations revealed no arteritis. Disparities between the usual patterns of clinical and anatomic involvement in giant cell arteritis underlie the potential diagnostic difficulties in this disease. Although typically diagnostic, temporal artery biopsy does not always bridge the clinical and anatomic disparities.
巨细胞动脉炎很少表现为临床上进展性的眼外缺血或坏疽。临床上孤立的腿部受累并需截肢的情况更为罕见。本文描述了一名69岁女性，她患有巨细胞动脉炎，需要双侧截肢。在四年的随访期内未出现其他临床后遗症。截肢后颞动脉活检未发现动脉炎。巨细胞动脉炎临床和解剖受累的常见模式之间的差异是该疾病潜在诊断困难的原因。虽然颞动脉活检通常具有诊断价值，但并不总能弥合临床和解剖上的差异。
